Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 110291..111063 Replicon chromosome
Accession NZ_CP054160
Organism Serratia fonticola strain HH13

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag G9399_RS00450 Protein ID WP_173410041.1
Coordinates 110291..110623 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag G9399_RS00455 Protein ID WP_173410040.1
Coordinates 110704..111063 (+) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9399_RS00420 (G9399_26290) 105366..105578 - 213 WP_173410046.1 AlpA family phage regulatory protein -
G9399_RS00425 (G9399_26285) 105706..106371 - 666 WP_173410045.1 inovirus Gp2 family protein -
G9399_RS00430 (G9399_26280) 107022..107972 + 951 WP_173410044.1 hypothetical protein -
G9399_RS00435 (G9399_26275) 108088..108906 + 819 WP_221035338.1 DUF932 domain-containing protein -
G9399_RS00440 (G9399_26270) 109315..109746 + 432 WP_173410043.1 antirestriction protein -
G9399_RS00445 (G9399_26265) 109762..110250 + 489 WP_173410042.1 DNA repair protein RadC -
G9399_RS00450 (G9399_26260) 110291..110623 + 333 WP_173410041.1 TA system toxin CbtA family protein Toxin
G9399_RS00455 (G9399_26255) 110704..111063 + 360 WP_173410040.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
G9399_RS00460 (G9399_26250) 111226..112080 + 855 WP_173410039.1 DUF4942 domain-containing protein -
G9399_RS00465 (G9399_26245) 112352..113311 - 960 WP_173410038.1 DUF5677 domain-containing protein -
G9399_RS00470 (G9399_26240) 113911..115128 + 1218 WP_221035339.1 potassium channel family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(9-103)

Antitoxin

Antitoxin CbeA

(17-116)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12576.35 Da        Isoelectric Point: 5.0744

>T158795 WP_173410041.1 NZ_CP054160:110291-110623 [Serratia fonticola]
MKTINTTIRIIPNPSAFTEYQQLLTWLLNHCYGLELNDTPYHDEQAIAQQIDNGVTVRETINELVDKFDLVRVDRPGFSL
LAQDPMLNDADLLRARSALGLRSPVNRRLI

Download         Length: 333 bp

>T158795 NZ_CP069840:c2323072-2322683 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13261.04 Da        Isoelectric Point: 6.4493

>AT158795 WP_173410040.1 NZ_CP054160:110704-111063 [Serratia fonticola]
MKEPVPNTINANDNTPIWGLQRAITPRLGARLVQQGNRLYFLADRAGFIGTFDPDALQMLDTAFPVLIEQLESRLRSGEL
DQRRQRCVTVQHAGFTCDADTLGSFGHVYIAIYPNQVSA

Download         Length: 360 bp

>AT158795 NZ_CP069840:c2323336-2323079 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References