Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 131313..131911 Replicon plasmid pB7.6
Accession NZ_CP054152
Organism Agrobacterium vaccinii strain B7.6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HRR99_RS22890 Protein ID WP_081880185.1
Coordinates 131313..131606 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HRR99_RS22895 Protein ID WP_233125019.1
Coordinates 131603..131911 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR99_RS22865 (HRR99_22810) 126693..127244 - 552 WP_111838605.1 TRAP transporter small permease -
HRR99_RS22870 (HRR99_22815) 127322..128317 - 996 WP_111838606.1 DctP family TRAP transporter solute-binding subunit -
HRR99_RS22875 (HRR99_22820) 128366..129253 - 888 WP_111838875.1 NAD(P)-dependent oxidoreductase -
HRR99_RS22880 (HRR99_22825) 129259..129573 - 315 WP_111838876.1 putative quinol monooxygenase -
HRR99_RS22885 (HRR99_22830) 129579..130937 - 1359 WP_111838607.1 SAF domain-containing protein -
HRR99_RS22890 (HRR99_22835) 131313..131606 - 294 WP_081880185.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HRR99_RS22895 (HRR99_22840) 131603..131911 - 309 WP_233125019.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HRR99_RS22900 (HRR99_22845) 131983..132384 - 402 WP_233125020.1 DUF2513 domain-containing protein -
HRR99_RS22905 (HRR99_22850) 132576..134891 + 2316 WP_233125021.1 hypothetical protein -
HRR99_RS22910 (HRR99_22855) 135141..135617 + 477 WP_233125022.1 VOC family protein -
HRR99_RS22915 (HRR99_22860) 135942..136790 - 849 WP_233125116.1 NAD(P)H-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..178559 178559


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-51)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10657.28 Da        Isoelectric Point: 5.8086

>T158794 WP_081880185.1 NZ_CP054152:c131606-131313 [Agrobacterium vaccinii]
MRLTWSAFALSDRDAIFTFIELENPAAAILVDERIVVAVRRLIDFPASGRVGRIAGTRELVISGTPYVAAYTITEATVRV
LRVLHGAQEWPEALSTS

Download         Length: 294 bp

>T158794 NZ_CP069840:c1571107-1570925 [Acinetobacter baumannii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11174.54 Da        Isoelectric Point: 4.6787

>AT158794 WP_233125019.1 NZ_CP054152:c131911-131603 [Agrobacterium vaccinii]
MAANALVQTRIDADVRDRASLVLEGMGLTVSDAVRILLTRTANEGVLPLELFSGSEAHDIWFRAKVLEALNDTRPDISDD
EVEAHFEKRRQAARNNAAGITS

Download         Length: 309 bp

>AT158794 NZ_CP069840:c1570832-1570428 [Acinetobacter baumannii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References