Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 2420073..2420661 Replicon chromosome
Accession NZ_CP054150
Organism Agrobacterium vaccinii strain B7.6

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HRR99_RS12000 Protein ID WP_233121879.1
Coordinates 2420356..2420661 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag HRR99_RS11995 Protein ID WP_233123492.1
Coordinates 2420073..2420363 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR99_RS11975 (HRR99_11945) 2415951..2416283 - 333 WP_045228458.1 HigA family addiction module antitoxin -
HRR99_RS11980 (HRR99_11950) 2416293..2416583 - 291 WP_045228457.1 type II toxin-antitoxin system RelE/ParE family toxin -
HRR99_RS11985 (HRR99_11955) 2416908..2418782 + 1875 WP_233121876.1 potassium/proton antiporter -
HRR99_RS11990 (HRR99_11960) 2418857..2420059 + 1203 WP_233121878.1 phosphoglycerate kinase -
HRR99_RS11995 (HRR99_11965) 2420073..2420363 - 291 WP_233123492.1 putative addiction module antidote protein Antitoxin
HRR99_RS12000 (HRR99_11970) 2420356..2420661 - 306 WP_233121879.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HRR99_RS12005 (HRR99_11975) 2420854..2421879 + 1026 WP_233121880.1 fructose-bisphosphate aldolase class I -
HRR99_RS12010 (HRR99_11980) 2422052..2423698 + 1647 WP_233121881.1 FAD-binding dehydrogenase -
HRR99_RS12015 (HRR99_11985) 2423695..2425503 - 1809 WP_233121882.1 ABC transporter transmembrane domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11296.04 Da        Isoelectric Point: 10.1497

>T158792 WP_233121879.1 NZ_CP054150:c2420661-2420356 [Agrobacterium vaccinii]
MIELRQTAVFVRWESRLRDKRARTLIAARLTRLAAGLPGDVEPVGEGVSELRIHHGPGYRIYFQQRGNLLIVLLCGGDKG
SQARDSAAAKKLAKEWILDDE

Download         Length: 306 bp

>T158792 NZ_CP069821:c5077003-5076635 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGACAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10244.72 Da        Isoelectric Point: 8.4830

>AT158792 WP_233123492.1 NZ_CP054150:c2420363-2420073 [Agrobacterium vaccinii]
MSKKLSTYDPAAALVDDEEIAAFMADAFETGDAAYVAKALGVVARAKGMTEISRKTGLSREQLYRSFSERGNPTLKTTLA
VMRALGVDMTAKAHSA

Download         Length: 291 bp

>AT158792 NZ_CP069821:c5077221-5077000 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References