Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/HTH(antitoxin)
Location 462401..462875 Replicon chromosome
Accession NZ_CP054150
Organism Agrobacterium vaccinii strain B7.6

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag HRR99_RS02215 Protein ID WP_233122592.1
Coordinates 462401..462664 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag HRR99_RS02220 Protein ID WP_233122593.1
Coordinates 462648..462875 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR99_RS02185 (HRR99_02185) 457740..459062 + 1323 WP_233122587.1 glycolate oxidase subunit GlcF -
HRR99_RS02190 (HRR99_02190) 459229..459951 - 723 WP_233122588.1 L,D-transpeptidase -
HRR99_RS02195 (HRR99_02195) 460141..460770 + 630 WP_233122589.1 DNA-3-methyladenine glycosylase I -
HRR99_RS02200 (HRR99_02200) 460767..461210 + 444 WP_233122590.1 hypothetical protein -
HRR99_RS02205 (HRR99_02205) 461219..461593 - 375 WP_233123547.1 DUF305 domain-containing protein -
HRR99_RS02210 (HRR99_02210) 461640..462404 - 765 WP_233122591.1 hypothetical protein -
HRR99_RS02215 (HRR99_02215) 462401..462664 - 264 WP_233122592.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HRR99_RS02220 (HRR99_02220) 462648..462875 - 228 WP_233122593.1 DUF6290 family protein Antitoxin
HRR99_RS02225 (HRR99_02225) 463032..464669 + 1638 WP_233122594.1 histidine--tRNA ligase -
HRR99_RS02230 (HRR99_02230) 464870..465991 + 1122 WP_233122595.1 ATP phosphoribosyltransferase regulatory subunit -
HRR99_RS02235 (HRR99_02235) 465988..466683 + 696 WP_233122596.1 ATP phosphoribosyltransferase -
HRR99_RS02240 (HRR99_02240) 466757..467203 - 447 WP_233122597.1 DoxX family protein -
HRR99_RS02245 (HRR99_02245) 467349..467864 - 516 WP_233122598.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Protein of unknown function DUF6290

(6-71)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10261.79 Da        Isoelectric Point: 8.9749

>T158787 WP_233122592.1 NZ_CP054150:c462664-462401 [Agrobacterium vaccinii]
VTWKIEYHSDFRTKVADIDPSLRHRIRSFLHEQVAVLDDPRKIGANLGNYWRYWESGLRLICDIHDQKRSILVIEIGHLP
KKSIAEP

Download         Length: 264 bp

>T158787 NZ_CP069821:c3504269-3504167 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8908.95 Da        Isoelectric Point: 4.6909

>AT158787 WP_233122593.1 NZ_CP054150:c462875-462648 [Agrobacterium vaccinii]
MSKQTAIRLPDDTYERLKALSERTGRTSTYYIREAIEKHIEDMEDLYLAEEATRQIQRGQSKIISAEEMWRDVEN

Download         Length: 228 bp

>AT158787 NZ_CP069821:3504160-3504305 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References