Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 809192..809790 Replicon chromosome
Accession NZ_CP054147
Organism Agrobacterium vaccinii strain B19.1.4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HRS00_RS18440 Protein ID WP_081880185.1
Coordinates 809192..809485 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HRS00_RS18445 Protein ID WP_233125019.1
Coordinates 809482..809790 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRS00_RS18420 (HRS00_18365) 804451..805365 + 915 WP_045231439.1 ABC transporter permease -
HRS00_RS18425 (HRS00_18370) 805446..806312 + 867 WP_162273343.1 ABC transporter permease -
HRS00_RS18430 (HRS00_18375) 806305..807924 + 1620 WP_233137212.1 ABC transporter ATP-binding protein -
HRS00_RS18435 (HRS00_18380) 807947..808843 + 897 WP_233137804.1 dihydrodipicolinate synthase family protein -
HRS00_RS18440 (HRS00_18385) 809192..809485 - 294 WP_081880185.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HRS00_RS18445 (HRS00_18390) 809482..809790 - 309 WP_233125019.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HRS00_RS18450 (HRS00_18395) 809862..810263 - 402 WP_233137213.1 DUF2513 domain-containing protein -
HRS00_RS18455 (HRS00_18400) 810450..812702 + 2253 WP_233137214.1 hypothetical protein -
HRS00_RS18460 (HRS00_18405) 813023..813385 - 363 WP_233125079.1 helix-turn-helix domain-containing protein -
HRS00_RS18465 (HRS00_18410) 813483..814229 + 747 WP_233125080.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-51)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10657.28 Da        Isoelectric Point: 5.8086

>T158783 WP_081880185.1 NZ_CP054147:c809485-809192 [Agrobacterium vaccinii]
MRLTWSAFALSDRDAIFTFIELENPAAAILVDERIVVAVRRLIDFPASGRVGRIAGTRELVISGTPYVAAYTITEATVRV
LRVLHGAQEWPEALSTS

Download         Length: 294 bp

>T158783 NZ_CP069821:719881-720165 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCAGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11174.54 Da        Isoelectric Point: 4.6787

>AT158783 WP_233125019.1 NZ_CP054147:c809790-809482 [Agrobacterium vaccinii]
MAANALVQTRIDADVRDRASLVLEGMGLTVSDAVRILLTRTANEGVLPLELFSGSEAHDIWFRAKVLEALNDTRPDISDD
EVEAHFEKRRQAARNNAAGITS

Download         Length: 309 bp

>AT158783 NZ_CP069821:719649-719891 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCAGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References