Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 1052174..1052718 Replicon chromosome
Accession NZ_CP054146
Organism Agrobacterium vaccinii strain B19.1.4

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HRS00_RS05155 Protein ID WP_233136318.1
Coordinates 1052395..1052718 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HRS00_RS05150 Protein ID WP_233136317.1
Coordinates 1052174..1052398 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRS00_RS05145 (HRS00_05135) 1051436..1052038 - 603 WP_233136316.1 hypothetical protein -
HRS00_RS05150 (HRS00_05140) 1052174..1052398 + 225 WP_233136317.1 antitoxin MazE family protein Antitoxin
HRS00_RS05155 (HRS00_05145) 1052395..1052718 + 324 WP_233136318.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
HRS00_RS05160 (HRS00_05150) 1052757..1053050 - 294 WP_111841244.1 transcriptional regulator -
HRS00_RS05165 (HRS00_05155) 1053572..1053943 + 372 WP_003507760.1 30S ribosomal protein S12 -
HRS00_RS05170 (HRS00_05160) 1054022..1054492 + 471 WP_062450738.1 30S ribosomal protein S7 -
HRS00_RS05175 (HRS00_05165) 1054520..1056619 + 2100 WP_111841246.1 elongation factor G -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-102)

Antitoxin

Antitoxin MazE-like

(6-70)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11597.60 Da        Isoelectric Point: 9.9229

>T158782 WP_233136318.1 NZ_CP054146:1052395-1052718 [Agrobacterium vaccinii]
VRRGDLVTVSVSGDFGKPRPALIIQSDYFLDTATVTVLLLSGTLFDAPFIRLTVQASPQNGLKKPSQVMIDKSMTVMREK
IGPVFGRLDDDVMLSVTRSLAVFVGLA

Download         Length: 324 bp

>T158782 NZ_CP069821:558103-558978 [Klebsiella pneumoniae]
ATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATTTGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGA
TTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGGTGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGG
ATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAGGCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAG
ATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAAGATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACC
ACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTTTTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCT
ACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCATCCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAG
GAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTATTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCC
TCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAATTCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGA
CAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCCTGTATCACACAACAGGATGTCGATTTTTTACTGTCATTTAAA
CGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCGTATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATAT
TCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAGATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8198.10 Da        Isoelectric Point: 5.0175

>AT158782 WP_233136317.1 NZ_CP054146:1052174-1052398 [Agrobacterium vaccinii]
VATSVNHRVQKRRDALRASGLRPVQIWVPDTRRPGFAEECLRQSKAVAVSDAFDTEFDAFADAALTDLDNEAPQ

Download         Length: 225 bp

>AT158782 NZ_CP069821:557297-558055 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References