158777

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/HTH(antitoxin)
Location 493334..493808 Replicon chromosome
Accession NZ_CP054146
Organism Agrobacterium vaccinii strain B19.1.4

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag HRS00_RS02340 Protein ID WP_233135956.1
Coordinates 493334..493597 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag HRS00_RS02345 Protein ID WP_233135957.1
Coordinates 493581..493808 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRS00_RS02310 (HRS00_02300) 488673..489995 + 1323 WP_233135951.1 glycolate oxidase subunit GlcF -
HRS00_RS02315 (HRS00_02305) 490162..490884 - 723 WP_233135952.1 L,D-transpeptidase -
HRS00_RS02320 (HRS00_02310) 491074..491703 + 630 WP_233135953.1 DNA-3-methyladenine glycosylase I -
HRS00_RS02325 (HRS00_02315) 491700..492143 + 444 WP_233135954.1 hypothetical protein -
HRS00_RS02330 (HRS00_02320) 492152..492526 - 375 WP_233136686.1 DUF305 domain-containing protein -
HRS00_RS02335 (HRS00_02325) 492573..493337 - 765 WP_233135955.1 hypothetical protein -
HRS00_RS02340 (HRS00_02330) 493334..493597 - 264 WP_233135956.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HRS00_RS02345 (HRS00_02335) 493581..493808 - 228 WP_233135957.1 DUF6290 family protein Antitoxin
HRS00_RS02350 (HRS00_02340) 493965..495578 + 1614 WP_233135958.1 histidine--tRNA ligase -
HRS00_RS02355 (HRS00_02345) 495779..496900 + 1122 WP_233135959.1 ATP phosphoribosyltransferase regulatory subunit -
HRS00_RS02360 (HRS00_02350) 496897..497592 + 696 WP_233135960.1 ATP phosphoribosyltransferase -
HRS00_RS02365 (HRS00_02355) 497650..498063 + 414 WP_233135961.1 GFA family protein -
HRS00_RS02370 (HRS00_02360) 498115..498561 - 447 WP_233135962.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Protein of unknown function DUF6290

(6-71)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10345.82 Da        Isoelectric Point: 8.0783

>T158777 WP_233135956.1 NZ_CP054146:c493597-493334 [Agrobacterium vaccinii]
VTWKIEYHSDFRTRITDIDPSLRHRIRSFLHDEVAVLDDPRKIGANLGNYWRYWESGLRFICDIQDQKRSILVIEIGHLP
KKSIAEP

Download         Length: 264 bp

>T158777 NZ_CP069815:4468500-4468718 [Raoultella planticola]
ATGTCTGGTGAACCATTAACCAAAACAGACTATTTGATGCGCTTACGTCGCTGTCAGACAATTGATACGCTGGAACGCGT
AATTGAAAAAAACAAATATGAACTTTCAGATAACGAACTGGCTGTATTTTACTCAGCGGCCGATCACCGTCTTGCTGAAT
TGACCATGAATAAACTCTACGACAAAATCCCGACATCGGTGTGGAAGTTCATTCGCTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8864.89 Da        Isoelectric Point: 4.6794

>AT158777 WP_233135957.1 NZ_CP054146:c493808-493581 [Agrobacterium vaccinii]
MSKQTAIRLPDDTYDRLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQIQRGQSKIISAEEMWRDVEN

Download         Length: 228 bp

>AT158777 NZ_CP069815:4468099-4468473 [Raoultella planticola]
ATGGACGAATACTCGCCAAAAAGACATGATATCGCGCAGCTTCGATTTCTTTGCGAAACCCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGTAACCACGGGTGGGTGAATGACCCGACGTCGGCTATCAATCTTCAACTTAATGAATTGATCGAAC
ACATAGCCACGTTCGCGCTTAATTATAAAATTAAGTATGCTGAGGATAATAAACTGATCGCTCAGCTGGACGAATACCTG
GATGACACTTTTATGTTGTTCAGCAGTTATGGCATTAACACGGCCGATCTACAGAAATGGCGCAAATCGGGAAATCGGTT
ATTCCGATGTTTTGTCAACGCCAGCCGGGAAAATCCGGCAAGTCTTTCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References