Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 5277962..5278518 Replicon chromosome
Accession NZ_CP054139
Organism Mucilaginibacter mali strain G2-14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HQ865_RS22380 Protein ID WP_173417040.1
Coordinates 5278180..5278518 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HQ865_RS22375 Protein ID WP_173417039.1
Coordinates 5277962..5278183 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ865_RS22360 5273216..5274085 + 870 WP_173417036.1 EamA family transporter -
HQ865_RS22365 5274277..5275761 + 1485 WP_173417037.1 hypothetical protein -
HQ865_RS22370 5276021..5277892 - 1872 WP_173417038.1 M1 family metallopeptidase -
HQ865_RS22375 5277962..5278183 + 222 WP_173417039.1 DUF433 domain-containing protein Antitoxin
HQ865_RS22380 5278180..5278518 + 339 WP_173417040.1 DUF5615 family PIN-like protein Toxin
HQ865_RS22385 5278736..5279455 + 720 WP_173417041.1 pyridoxine 5'-phosphate synthase -
HQ865_RS22390 5279553..5282462 + 2910 WP_173417042.1 aminomethyl-transferring glycine dehydrogenase -
HQ865_RS22395 5282548..5282916 + 369 WP_173417043.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-79)

Antitoxin

Protein of unknown function DUF433

(7-62)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12447.51 Da        Isoelectric Point: 4.7045

>T158770 WP_173417040.1 NZ_CP054139:5278180-5278518 [Mucilaginibacter mali]
MKIWVDAQLSPVIALWINESFTDINAVSMRSLDMLYASDIDIFKAARAQSVVILSKDADFVKLIELHGIPPQLIWVTCGN
TSNSRMFQILKTALPQAKQLLESGEQIVEIGS

Download         Length: 339 bp

>T158770 NZ_CP069812:1937559-1938887 [Cupriavidus oxalaticus]
ATGACGCGCGGCACGCACGCGAAGCGTCTCGACCTGTGGATGAACGGCTTGCCGGTGGGTCACTGGGAAACCGCGCCCGC
CGGCGACCGGCTGGCCTATCGCGAAGACTGGATTGCCGACCCGCAAGGCCGGCCGCTGTCCTTGTCATTGCCCTTTACGC
CGGGCAACCAGCCACACCGCGGACCGGTAGTCGCCAACTATTTCGACAACCTGCTGCCCGACAGCGATGCCATCAGGCGG
CGCATCGCGGCCCGGTATCAGACCGGCGGGACCGACGCCTTCGCGCTGCTGGCCAGGCTCGGCCGCGACTGCGCCGGCGC
CCTGCAGATGCTGCCGCCGCAGGAAGCGCCGATGGCGTTGAAGCGCGTCCAGGGCCGCCCGCTGTCGGAGACGGAGATCG
CCACCCTGCTGCACGAGGCCACGGCCGAGCCCGTGCTCGGGCTGCGCGAGCCTATCGATGACCTGCGCCTGTCAATTGCC
GGCGCACAGGAAAAGACCGCGCTGCTGCGCTGGGACGGGCAATGGCTGTTGCCGCAAGGCAGTACGCCGACCACGCATAT
CTTCAAGCTGCCCATGGGACTGGTGGGCAATATGCGCGCCGACATGCGGACCTCGGTGGAAAACGAATGGCTCTGCGCCA
GGATCGTCGCCGCGTTTGGCCTGCCGGTCGCTGCCTGCGAGATCGCCCGCTTCGGGGATACCAAGGCGCTGGTCGTCGAA
CGCTTCGACCGCAAGCCCTCGGCAGACGGTTCCTGGCTGCTGCGCCTGCCGCAGGAAGACATGTGCCAGGCCACCGGGAC
GTCGGCATTGCAGAAGTACGAGTCGGACGGCGGGCCTGGCATCCAGCAGATCGCAGACATCCTCTCGGGCTCGCGCTCGG
CGCTGTCCGATCGCCGCAACTTCTTCCTCGCGCAGATCGTCTTCTGGCTGCTCGCGGCCACGGATGGACATGGCAAGAAC
TTCAGCATCAGCCACCTGCCGGGCAGCCGATATGAGGCGACGCCGCTGTATGACATCCTGTCGGCGCATCCGATCATCGG
CAAAGGCAAGAACCAGGTGGCGCCGCAACGGGCCCGGCTGGCGATGGCGTTGCACGGCAAGAATTCGCACTACGCCATCC
AGGAGATCCAGCGGCGGCACTGGTTTGCCCAGGGACAGCGCATCGGCTTCTCGCCCGACGATGTCGAGTCGATGCTCGAC
GAGGTCATGTCGCAGACCAGCCGGGCTATCGACGCCGCCGCTTCCGCGCTGCCGCCGGAATTCCCCATGGACCTGGCCGA
TGCGATCTTCGATGGCATGCGCCGGCAGCAGCGGCGCCTGGCCGCCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8172.53 Da        Isoelectric Point: 4.7360

>AT158770 WP_173417039.1 NZ_CP054139:5277962-5278183 [Mucilaginibacter mali]
MSWKERITVNLLQCGGRPCIRGMRIRVIDVLDLLASGLTQEQVLEELPDLEKEDIEAALKYAGSRLDHPIIAA

Download         Length: 222 bp

>AT158770 NZ_CP069812:1937176-1937556 [Cupriavidus oxalaticus]
ATGCACTATTCCATCCAGACACTCAGCCAGTTGCGGCCGATCCTGCAGGGCTTCCGGAAGTCCAGGGGCCTGACGCAGGC
AAATATGGCGGCTTACCTCGGCGTCAGGCAGCAGACCTATGCCGAACTGGAAGCCAACCCTGCCGCGGCCAGCGTAGAGC
GGCTGTTCAAGGCGCTGCGCGTGCTGGGCGTGGAGATGGTCCTTTCCCCTGCTCCAGATACCGCCATGCAGCCGGAACCG
GAGCCTCCTTCCGGCTCCGTGACGCCGCCGGAAAAGGATCCGCGCCGGGCTACACAGGAAGAACAGCCGAAAATGCCCGC
GAAGCGCAAGGCAAGCCGCACCGCCCTCGAGACCGGTCAGCCAAAGCGGGAGGACTGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References