Detailed information of TA system TA158764

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 459894..460547
• Replicon: chromosome
• Accession: NZ_CP054137
• Organism: Acinetobacter pittii strain JXA13

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: HRJ47_RS02260
• Protein ID: WP_086399324.1
• Coordinates: 460158..460547 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A009HHW9
• Locus tag: HRJ47_RS02255
• Protein ID: WP_002117064.1
• Coordinates: 459894..460151 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HRJ47_RS02235	455407..456414	+	1008	WP_002116730.1	DNA-directed RNA polymerase subunit alpha	-
HRJ47_RS02240	456433..456810	+	378	WP_002049717.1	50S ribosomal protein L17	-
HRJ47_RS02245	456992..458482	+	1491	WP_002116796.1	NAD(P)/FAD-dependent oxidoreductase	-
HRJ47_RS02250	458533..459705	-	1173	WP_017386981.1	acyl-CoA dehydrogenase family protein	-
HRJ47_RS02255	459894..460151	+	258	WP_002117064.1	succinate dehydrogenase assembly factor 2	Antitoxin
HRJ47_RS02260	460158..460547	+	390	WP_086399324.1	hypothetical protein	Toxin
HRJ47_RS02265	461318..462406	+	1089	WP_014207738.1	hypothetical protein	-
HRJ47_RS02270	462491..463066	+	576	WP_140157903.1	rhombosortase	-
HRJ47_RS02275	463246..465441	+	2196	WP_017400431.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15586.65 Da
• Isoelectric Point: 6.3102

>T158764 WP_086399324.1 NZ_CP054137:460158-460547 [Acinetobacter pittii]
MIKELNFELKYSRVSVVFQLFVGLGLAILLYQLLTPMWWLCAVILLFIGFIFFLKQVQISQIEYLDQKLWSVAYFSEKEI
YRAEITKIIDYQLFVVIYFEETPTNIAIVWFDQLPIQQWKRLKVLEKLY

Nucleotide

• Length: 390 bp

>T158764 NZ_CP069810:c3116633-3116262 [Cupriavidus oxalaticus]
ATGATCCTGGTCGACACCTCGGTATGGATCGACCATCTGCGTACCGGCGACGCGGCACTAGCGGCTTTGCTCGACGCCAG
CCGGGTCCTGGTGCATCCGTTTGTGATCGGCGAGATCGCGCTGGGTAGCCTGCGGCAGCGGGGCGAGGTGCTGGGCGCTT
TGCGTGATTTGCCAGGCGCCGTCGTGGCGACGGACGACGAAGTCGACCGGATGATCGATGACCAGAAGTTGTACGGGATA
GGGATTGGCTACGTGGATGCGCATCTGCTGGCCGCCACCCGATTGACGCCCGGCAGTGCGCTATGGACGCGGGATCGTCG
CCTGCTCGCGGTCGCCGAGCATTTGGGGCTGGCCGCGCGGCCTGCGCATTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10295.73 Da
• Isoelectric Point: 4.4809

>AT158764 WP_002117064.1 NZ_CP054137:459894-460151 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Nucleotide

• Length: 258 bp

>AT158764 NZ_CP069810:c3116827-3116630 [Cupriavidus oxalaticus]
ATGCGCACCACGCTTGCCCTGGACGATGATTTGCTGCGCAAGGCCCAGGCCCTGACCGGCCTGTCCGAAAAATCCTCGCT
CGTGCGCGAAGCGCTGCGGGCACTGATCGAGCGCGAAAGCGCGCGCCGCCTGAGCCGTCTCGGCGGTACCGAACCCGACC
TGGAATCCGCGCCGCGCCGCCGCGCGGAGCCGGCATGA

Structures

Antitoxin

• AlphaFold DB: A0A009HHW9