Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 865668..866322 Replicon chromosome
Accession NZ_CP054129
Organism Citrobacter portucalensis strain BY9F36

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HRV88_RS04170 Protein ID WP_003825515.1
Coordinates 865915..866322 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HRV88_RS04165 Protein ID WP_003825514.1
Coordinates 865668..865934 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRV88_RS04140 (HRV88_04140) 860823..862256 - 1434 WP_008785745.1 6-phospho-beta-glucosidase BglA -
HRV88_RS04145 (HRV88_04145) 862377..863105 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
HRV88_RS04150 (HRV88_04150) 863158..863469 + 312 WP_008785743.1 N(4)-acetylcytidine aminohydrolase -
HRV88_RS04155 (HRV88_04155) 863633..864295 + 663 WP_071445549.1 hemolysin III family protein -
HRV88_RS04160 (HRV88_04160) 864427..865410 - 984 WP_008785741.1 tRNA-modifying protein YgfZ -
HRV88_RS04165 (HRV88_04165) 865668..865934 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
HRV88_RS04170 (HRV88_04170) 865915..866322 + 408 WP_003825515.1 protein YgfX Toxin
HRV88_RS04175 (HRV88_04175) 866424..866945 - 522 WP_003026933.1 flavodoxin FldB -
HRV88_RS04180 (HRV88_04180) 867059..867955 + 897 WP_186413019.1 site-specific tyrosine recombinase XerD -
HRV88_RS04185 (HRV88_04185) 867979..868692 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HRV88_RS04190 (HRV88_04190) 868698..870431 + 1734 WP_218658953.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T158745 WP_003825515.1 NZ_CP054129:865915-866322 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T158745 NZ_CP069798:c1169995-1169741 [Paralysiella testudinis]
ATGGATACCATGAGCTACTCTGCTTTCCGCGCCGGATTGGCCGGGGTGCTGGATAAGGTCAACGACAACCACAAGCCGGT
TTTGGTAACCCGCCAAAACGGTAAACCGGCCGTGGTCATGAGTTTGGAAGATTTTCAGTCTTACGAAGAAACCGCCTACC
TGATGGCCAGCCCAGCCAATGCCGAGCGACTGAACCGGGCAGTGGCACAGATTCGCGCCGGTGAAGCACAACAACACGGG
ATGCTGGAAGAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT158745 WP_003825514.1 NZ_CP054129:865668-865934 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT158745 NZ_CP069798:c1169744-1169481 [Paralysiella testudinis]
ATGATGCTGGCGTGGGCCGATGATGCTTGGAACGATTATATGTATTGGCAACAAACCGATAAACGCATGCTGAAACGCAT
CAATATGCTGCTGAAAGGCATTCAGCGCCAGCCATTTGCTGGATTGGGGGATCCTGAGCCGCTGAAGCACAATTGGTCAG
GCTTTTGGTCGCGCCGCATCAACAAAGAACACCGGCTGGTTTACCGCGTGAGTAATGATAGGGTGATGGTGGCGCAATGC
CGTTACCATTATGGCAAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References