Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1865725..1865870 Replicon chromosome
Accession NZ_CP054063
Organism Klebsiella pneumoniae strain WSHvKP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1865761..1865863 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1865725..1865870 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ868_RS09065 1860855..1862915 + 2061 WP_004151449.1 oligopeptidase B -
HQ868_RS09070 1862919..1863578 - 660 WP_002911407.1 exodeoxyribonuclease X -
HQ868_RS09075 1863657..1863887 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HQ868_RS09080 1864000..1864374 + 375 WP_048279882.1 CopC domain-containing protein YobA -
HQ868_RS09085 1864378..1865247 + 870 WP_048279880.1 copper homeostasis membrane protein CopD -
HQ868_RS09090 1865264..1865602 + 339 WP_002911404.1 YebY family protein -
- 1865725..1865870 - 146 - - Antitoxin
- 1865761..1865863 + 103 - - Toxin
HQ868_RS09095 1866238..1866381 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HQ868_RS09100 1866486..1867454 - 969 WP_004151446.1 VirK/YbjX family protein -
HQ868_RS09105 1867611..1868264 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
HQ868_RS09110 1868261..1868452 - 192 WP_002911395.1 YebW family protein -
HQ868_RS09115 1868550..1868789 - 240 WP_002911393.1 YebV family protein -
HQ868_RS09120 1868905..1870338 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T158639 NZ_CP054063:1865761-1865863 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT158639 NZ_CP054063:c1865870-1865725 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References