Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4499296..4499818 Replicon chromosome
Accession NZ_CP054058
Organism Scandinavium goeteborgense strain CCUG 66741

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag A8O29_RS22245 Protein ID WP_125353056.1
Coordinates 4499531..4499818 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag A8O29_RS22240 Protein ID WP_125353057.1
Coordinates 4499296..4499538 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8O29_RS22220 4495635..4496537 + 903 WP_110511892.1 formate dehydrogenase subunit beta -
A8O29_RS22225 4496534..4497169 + 636 WP_125353062.1 formate dehydrogenase cytochrome b556 subunit -
A8O29_RS22230 4497166..4498095 + 930 WP_125353060.1 formate dehydrogenase accessory protein FdhE -
A8O29_RS22235 4498323..4499231 + 909 WP_125353058.1 alpha/beta hydrolase -
A8O29_RS22240 4499296..4499538 + 243 WP_125353057.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
A8O29_RS22245 4499531..4499818 + 288 WP_125353056.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A8O29_RS22250 4499819..4500760 - 942 WP_159466029.1 fatty acid biosynthesis protein FabY -
A8O29_RS22255 4500805..4501242 - 438 WP_110511896.1 D-tyrosyl-tRNA(Tyr) deacylase -
A8O29_RS22260 4501239..4502111 - 873 WP_125353054.1 virulence factor BrkB family protein -
A8O29_RS22265 4502105..4502704 - 600 WP_125353053.1 glucose-1-phosphatase -
A8O29_RS22270 4502920..4504746 - 1827 WP_125353052.1 ribosome-dependent GTPase TypA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-90)

Antitoxin

Antitoxin ParD

(1-67)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11123.62 Da        Isoelectric Point: 6.3192

>T158627 WP_125353056.1 NZ_CP054058:4499531-4499818 [Scandinavium goeteborgense]
MYKLSNLAAEDFSSVYEYTWRRFGPQQADKYTAELDSLLILLANNPQMGRDCANLIEGVRRHEHGQHAIFYQYADNGIFI
IRILHQQMNPELHLL

Download         Length: 288 bp

>T158627 NZ_CP069706:2659874-2659981 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9055.17 Da        Isoelectric Point: 5.8670

>AT158627 WP_125353057.1 NZ_CP054058:4499296-4499538 [Scandinavium goeteborgense]
MPRTTSITIGEQLDRFINEMIESGRYGSTSEVVRSALRLLEEQELRNGQLRDALEEGLRSGESPHTLNEIAARKKRSLNV

Download         Length: 243 bp

>AT158627 NZ_CP069706:c2659827-2659761 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References