Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2893832..2894358 Replicon chromosome
Accession NZ_CP054058
Organism Scandinavium goeteborgense strain CCUG 66741

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A8O29_RS14850 Protein ID WP_125355650.1
Coordinates 2893832..2894119 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A8O29_RS14855 Protein ID WP_125355652.1
Coordinates 2894119..2894358 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8O29_RS14835 2889106..2890308 + 1203 WP_125355646.1 nicotinate phosphoribosyltransferase -
A8O29_RS14840 2890480..2891880 + 1401 WP_110509884.1 asparagine--tRNA ligase -
A8O29_RS14845 2892487..2893659 + 1173 WP_168713900.1 porin -
A8O29_RS14850 2893832..2894119 - 288 WP_125355650.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A8O29_RS14855 2894119..2894358 - 240 WP_125355652.1 type II toxin-antitoxin system antitoxin RelB Antitoxin
A8O29_RS14860 2894565..2895155 + 591 WP_056780970.1 GrpB family protein -
A8O29_RS14865 2895252..2895701 + 450 WP_125355658.1 GNAT family N-acetyltransferase -
A8O29_RS14870 2895876..2896346 + 471 WP_125355654.1 GNAT family N-acetyltransferase -
A8O29_RS14875 2896468..2897100 + 633 WP_125355656.1 Vat family streptogramin A O-acetyltransferase -
A8O29_RS14880 2897587..2898362 + 776 Protein_2770 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-78)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11184.21 Da        Isoelectric Point: 10.4221

>T158622 WP_125355650.1 NZ_CP054058:c2894119-2893832 [Scandinavium goeteborgense]
MVYLLDFDERALKEWHKLGATVREQLKKKLAEVLKSPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVVSVGK
RERSDVYTEAVKRIR

Download         Length: 288 bp

>T158622 NZ_CP069706:1451785-1452183 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGGTGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTAACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9057.45 Da        Isoelectric Point: 4.5112

>AT158622 WP_125355652.1 NZ_CP054058:c2894358-2894119 [Scandinavium goeteborgense]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDDL

Download         Length: 240 bp

>AT158622 NZ_CP069706:1451558-1451785 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References