Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 779562..780219 Replicon chromosome
Accession NZ_CP054058
Organism Scandinavium goeteborgense strain CCUG 66741

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag A8O29_RS04520 Protein ID WP_125352809.1
Coordinates 779809..780219 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag A8O29_RS04515 Protein ID WP_110511985.1
Coordinates 779562..779828 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8O29_RS04490 775137..775955 - 819 WP_125352878.1 hypothetical protein -
A8O29_RS04495 776313..776627 - 315 WP_125352814.1 AzlD domain-containing protein -
A8O29_RS04500 776628..777293 - 666 WP_125352876.1 AzlC family ABC transporter permease -
A8O29_RS04505 777436..778260 - 825 WP_125352812.1 AraC family transcriptional regulator -
A8O29_RS04510 778331..779314 - 984 WP_125352811.1 tRNA-modifying protein YgfZ -
A8O29_RS04515 779562..779828 + 267 WP_110511985.1 FAD assembly factor SdhE Antitoxin
A8O29_RS04520 779809..780219 + 411 WP_125352809.1 protein YgfX Toxin
A8O29_RS04525 780227..780748 - 522 WP_125352807.1 flavodoxin FldB -
A8O29_RS04530 780847..781743 + 897 WP_125352805.1 site-specific tyrosine recombinase XerD -
A8O29_RS04535 781772..782485 + 714 WP_125352803.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
A8O29_RS04540 782491..784224 + 1734 WP_125352801.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16042.90 Da        Isoelectric Point: 11.5608

>T158610 WP_125352809.1 NZ_CP054058:779809-780219 [Scandinavium goeteborgense]
VVLWQSDLRVSWRAQWVSLLLHGLVAAFILLMPWPLSFTPLWLLLLSLVVFDCVRSQRRINATQGEIKLLMDSRLRWQNQ
EWDLLGTPWVLNSGMMLRLRRVDGRKKAHLWLAADSMDTGEWRDLRRTILQQPAQQ

Download         Length: 411 bp

>T158610 NZ_CP069695:c9725-9474 [Escherichia coli H20]
ATGAGAAAAAATAAAGGTGATGTGACTTATTTTCTTGAAAAAGAAGGTGACAATTACAGGCTTACAAAAAGGATAAAAGC
CAGAACAAATGTTAAAATCGGGAACAAAACTACGAAAATTACATTGTATGATGCTGTACTGAATGAGAATGAATTACAAC
ATATTGATTTTACGTGTGCCGGATTAAGGGAAGACGATGAGACGCCAGTTAAGAATTTAATTAAGGAGTTTATGTTAAAT
GAAACCCGATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10444.00 Da        Isoelectric Point: 5.1114

>AT158610 WP_110511985.1 NZ_CP054058:779562-779828 [Scandinavium goeteborgense]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDGDKALFIRLLECDDPDLFNWLMNHGKPADAEMQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT158610 NZ_CP069695:c9487-9260 [Escherichia coli H20]
ATGAAACCCGATAATACACCTGAAAATGTAAAAAAATTACGTTTAAAAGCAGGATTAACACAAAAGGAATGCAGTCATAT
TTATGGTGTTGGGCTAAGAACCTGGCAGAAAAAAGAGGAAGTTAATACTCAAAACAGTCAAAGTCTGTCACTGGTTGAGT
TTGAGTTTCTTTTGTTACTTGCAGGAGAACATCCTGAATACGTGCTCTGCAAAAGGGAGTCAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References