Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
Location | 144682..145232 | Replicon | chromosome |
Accession | NZ_CP054058 | ||
Organism | Scandinavium goeteborgense strain CCUG 66741 |
Toxin (Protein)
Gene name | ccdB | Uniprot ID | - |
Locus tag | A8O29_RS01430 | Protein ID | WP_125354354.1 |
Coordinates | 144924..145232 (+) | Length | 103 a.a. |
Antitoxin (Protein)
Gene name | ccdA | Uniprot ID | - |
Locus tag | A8O29_RS01425 | Protein ID | WP_125354353.1 |
Coordinates | 144682..144921 (+) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A8O29_RS01405 | 139939..140241 | + | 303 | WP_125354350.1 | YsaB family lipoprotein | - |
A8O29_RS01410 | 140390..141301 | + | 912 | WP_110510263.1 | glycine--tRNA ligase subunit alpha | - |
A8O29_RS01415 | 141311..143380 | + | 2070 | WP_125354351.1 | glycine--tRNA ligase subunit beta | - |
A8O29_RS01420 | 143522..143980 | - | 459 | WP_125354352.1 | hypothetical protein | - |
A8O29_RS01425 | 144682..144921 | + | 240 | WP_125354353.1 | type II toxin-antitoxin system CcdA family antitoxin | Antitoxin |
A8O29_RS01430 | 144924..145232 | + | 309 | WP_125354354.1 | CcdB family protein | Toxin |
A8O29_RS01435 | 145429..147051 | + | 1623 | WP_125354355.1 | ATP-binding cassette domain-containing protein | - |
A8O29_RS01440 | 147090..147380 | - | 291 | WP_110510257.1 | HTH-type transcriptional regulator | - |
A8O29_RS01445 | 147756..149123 | - | 1368 | WP_125354356.1 | MFS transporter | - |
A8O29_RS01450 | 149515..150225 | + | 711 | WP_110510255.1 | DUF3053 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11865.71 Da Isoelectric Point: 5.7902
>T158607 WP_125354354.1 NZ_CP054058:144924-145232 [Scandinavium goeteborgense]
MQYVVYRNNGNSQVYPFLLDVQSDIIEELTTRVVIPLYPLSRLTTKPVRRLTPILNIEGNDYLVMTHEMASIRLTQIGDE
VMNARPYRQTIKNALDFIFDGF
MQYVVYRNNGNSQVYPFLLDVQSDIIEELTTRVVIPLYPLSRLTTKPVRRLTPILNIEGNDYLVMTHEMASIRLTQIGDE
VMNARPYRQTIKNALDFIFDGF
Download Length: 309 bp
>T158607 NZ_CP069693:66099-66515 [Escherichia coli H20]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCTGAAGCAGTGCTTAAGAATCT
GGAGCAGGCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGTC
CAAAGGCATCGCCACGCCACGTGCAGCTGGTTGACGCGTTCTGCGCCCGTCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGATGCAACCACGGAGGTTAAGGTGGCGCTGCGCCTCGCCGGCACGCCGATCGGTCCAAACGACACGGCGATCGC
CGGGCACGCCATCGCCACCGGGGCAATACTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTGCCTGGACTGGTACTGG
AAGACTGGGCAGGATAA
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCTGAAGCAGTGCTTAAGAATCT
GGAGCAGGCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGTC
CAAAGGCATCGCCACGCCACGTGCAGCTGGTTGACGCGTTCTGCGCCCGTCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGATGCAACCACGGAGGTTAAGGTGGCGCTGCGCCTCGCCGGCACGCCGATCGGTCCAAACGACACGGCGATCGC
CGGGCACGCCATCGCCACCGGGGCAATACTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTGCCTGGACTGGTACTGG
AAGACTGGGCAGGATAA
Antitoxin
Download Length: 80 a.a. Molecular weight: 8738.85 Da Isoelectric Point: 5.7929
>AT158607 WP_125354353.1 NZ_CP054058:144682-144921 [Scandinavium goeteborgense]
MPGMSVRHKKTVSVTLEPALLQQAREAGINLSAVLTAALQQEISASGAERWKQENRAGLQELNRITDEQGLLSDDYRTF
MPGMSVRHKKTVSVTLEPALLQQAREAGINLSAVLTAALQQEISASGAERWKQENRAGLQELNRITDEQGLLSDDYRTF
Download Length: 240 bp
>AT158607 NZ_CP069693:65872-66102 [Escherichia coli H20]
ATGAGAACCGTATCTATTTTCAAAAATGGCAATAACCGCGCGATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAGATTGTACGGGAAGGGGACAGAATCATTCTGCGTCCCCTCCGCCCGAGCTGGAGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGGCTTTATGACGGAACGCGAGGACGTTGTCTGCGACGAAGGACGATTTAACCTGTGA
ATGAGAACCGTATCTATTTTCAAAAATGGCAATAACCGCGCGATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAGATTGTACGGGAAGGGGACAGAATCATTCTGCGTCCCCTCCGCCCGAGCTGGAGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGGCTTTATGACGGAACGCGAGGACGTTGTCTGCGACGAAGGACGATTTAACCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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