Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 144682..145232 Replicon chromosome
Accession NZ_CP054058
Organism Scandinavium goeteborgense strain CCUG 66741

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag A8O29_RS01430 Protein ID WP_125354354.1
Coordinates 144924..145232 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag A8O29_RS01425 Protein ID WP_125354353.1
Coordinates 144682..144921 (+) Length 80 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8O29_RS01405 139939..140241 + 303 WP_125354350.1 YsaB family lipoprotein -
A8O29_RS01410 140390..141301 + 912 WP_110510263.1 glycine--tRNA ligase subunit alpha -
A8O29_RS01415 141311..143380 + 2070 WP_125354351.1 glycine--tRNA ligase subunit beta -
A8O29_RS01420 143522..143980 - 459 WP_125354352.1 hypothetical protein -
A8O29_RS01425 144682..144921 + 240 WP_125354353.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
A8O29_RS01430 144924..145232 + 309 WP_125354354.1 CcdB family protein Toxin
A8O29_RS01435 145429..147051 + 1623 WP_125354355.1 ATP-binding cassette domain-containing protein -
A8O29_RS01440 147090..147380 - 291 WP_110510257.1 HTH-type transcriptional regulator -
A8O29_RS01445 147756..149123 - 1368 WP_125354356.1 MFS transporter -
A8O29_RS01450 149515..150225 + 711 WP_110510255.1 DUF3053 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-101)

Antitoxin

(9-79)


Sequences


Toxin        


Download         Length: 103 a.a.        Molecular weight: 11865.71 Da        Isoelectric Point: 5.7902

>T158607 WP_125354354.1 NZ_CP054058:144924-145232 [Scandinavium goeteborgense]
MQYVVYRNNGNSQVYPFLLDVQSDIIEELTTRVVIPLYPLSRLTTKPVRRLTPILNIEGNDYLVMTHEMASIRLTQIGDE
VMNARPYRQTIKNALDFIFDGF

Download         Length: 309 bp

>T158607 NZ_CP069693:66099-66515 [Escherichia coli H20]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCTGAAGCAGTGCTTAAGAATCT
GGAGCAGGCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGTC
CAAAGGCATCGCCACGCCACGTGCAGCTGGTTGACGCGTTCTGCGCCCGTCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGATGCAACCACGGAGGTTAAGGTGGCGCTGCGCCTCGCCGGCACGCCGATCGGTCCAAACGACACGGCGATCGC
CGGGCACGCCATCGCCACCGGGGCAATACTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTGCCTGGACTGGTACTGG
AAGACTGGGCAGGATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8738.85 Da        Isoelectric Point: 5.7929

>AT158607 WP_125354353.1 NZ_CP054058:144682-144921 [Scandinavium goeteborgense]
MPGMSVRHKKTVSVTLEPALLQQAREAGINLSAVLTAALQQEISASGAERWKQENRAGLQELNRITDEQGLLSDDYRTF

Download         Length: 240 bp

>AT158607 NZ_CP069693:65872-66102 [Escherichia coli H20]
ATGAGAACCGTATCTATTTTCAAAAATGGCAATAACCGCGCGATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAGATTGTACGGGAAGGGGACAGAATCATTCTGCGTCCCCTCCGCCCGAGCTGGAGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGGCTTTATGACGGAACGCGAGGACGTTGTCTGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References