Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 55720..56465 Replicon chromosome
Accession NZ_CP054056
Organism Aquiluna borgnonia strain 15G-AUS-rot

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag HRU87_RS00325 Protein ID WP_173492994.1
Coordinates 55720..56202 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag HRU87_RS00330 Protein ID WP_173492995.1
Coordinates 56199..56465 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRU87_RS00290 51637..51876 + 240 WP_173492987.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
HRU87_RS00295 51873..52256 + 384 WP_173492988.1 PIN domain-containing protein -
HRU87_RS00300 52265..53221 + 957 WP_173492989.1 aldo/keto reductase -
HRU87_RS00305 53222..53773 - 552 WP_173492990.1 TIGR00645 family protein -
HRU87_RS00310 53923..54195 + 273 WP_213086395.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
HRU87_RS00315 54192..54590 + 399 WP_173492992.1 type II toxin-antitoxin system VapC family toxin -
HRU87_RS00320 54618..55628 - 1011 WP_173492993.1 prolyl oligopeptidase family serine peptidase -
HRU87_RS00325 55720..56202 - 483 WP_173492994.1 GNAT family N-acetyltransferase Toxin
HRU87_RS00330 56199..56465 - 267 WP_173492995.1 DUF1778 domain-containing protein Antitoxin
HRU87_RS00335 56703..57227 + 525 WP_173492996.1 excalibur calcium-binding domain-containing protein -
HRU87_RS00340 57230..57913 + 684 WP_173492997.1 hypothetical protein -
HRU87_RS00345 57959..58162 + 204 WP_173492998.1 hypothetical protein -
HRU87_RS00350 58309..59964 + 1656 WP_173492999.1 choice-of-anchor I family protein -
HRU87_RS00355 60170..60937 + 768 WP_213086396.1 DUF1524 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(40-143)

Antitoxin

Vibrio phage ICP1, Orf50

(6-74)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17254.12 Da        Isoelectric Point: 7.3840

>T158604 WP_173492994.1 NZ_CP054056:c56202-55720 [Aquiluna borgnonia]
MTKPEPLGPEHHLWGFDCGSNVINSWLQNSALKAQLANSSRTFVVLSDKKVVGFFSLATASLLYAELPQAQRNNLGQHPV
PMMLLTRMGVDKSFQHLGLGAAMVKDAVIKCLAVQQAAGLVGLMAHALDESVAEFYLKLGFERSPANPLLLSLGLLLQGD

Download         Length: 483 bp

>T158604 NZ_CP069692:c4787382-4787071 [Escherichia coli H20]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9994.19 Da        Isoelectric Point: 4.6909

>AT158604 WP_173492995.1 NZ_CP054056:c56465-56199 [Aquiluna borgnonia]
MAKEERIHIRATSEQKQLLARASQIRGRSVSDFVLESAVEEATNALLDQRVFVFSEEDYDAFLTRANDVEKNREVIAGIL
NVKSPWEG

Download         Length: 267 bp

>AT158604 NZ_CP069692:c4787070-4786780 [Escherichia coli H20]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References