Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1388545..1389059 Replicon chromosome
Accession NZ_CP054052
Organism Poseidonibacter lekithochrous strain DSM 100870

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ALEK_RS06675 Protein ID WP_071625932.1
Coordinates 1388545..1388811 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ALEK_RS06680 Protein ID WP_071625931.1
Coordinates 1388811..1389059 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ALEK_RS06650 1383724..1384713 + 990 WP_071625936.1 cysteine desulfurase -
ALEK_RS06655 1384703..1385950 + 1248 WP_071625935.1 molybdopterin molybdotransferase MoeA -
ALEK_RS06660 1386053..1386793 + 741 WP_197950392.1 substrate-binding domain-containing protein -
ALEK_RS06665 1386825..1387520 + 696 WP_071625933.1 ABC transporter permease -
ALEK_RS06670 1387517..1388542 + 1026 WP_083574587.1 energy-coupling factor ABC transporter ATP-binding protein -
ALEK_RS06675 1388545..1388811 - 267 WP_071625932.1 type II toxin-antitoxin system YafQ family toxin Toxin
ALEK_RS06680 1388811..1389059 - 249 WP_071625931.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ALEK_RS06685 1389155..1390039 - 885 WP_071625930.1 hypothetical protein -
ALEK_RS06690 1390065..1390946 - 882 WP_071625929.1 DUF4231 domain-containing protein -
ALEK_RS06695 1390946..1391356 - 411 WP_071625928.1 TIR domain-containing protein -
ALEK_RS06700 1391598..1391885 - 288 WP_071625927.1 type II toxin-antitoxin system RelE/ParE family toxin -
ALEK_RS06705 1391875..1392126 - 252 WP_071625926.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
ALEK_RS06710 1392394..1393062 + 669 WP_071625925.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10490.29 Da        Isoelectric Point: 9.6104

>T158598 WP_071625932.1 NZ_CP054052:c1388811-1388545 [Poseidonibacter lekithochrous]
MLLKRHKYFRKDEIKVKLTDEQYTKRIKYLSCILQGKELPSESRDHALLGDYKGMREFHLGGDMLLIYTVIDDVLYLQRL
GTHSQLFK

Download         Length: 267 bp

>T158598 NZ_CP069692:3650967-3651185 [Escherichia coli H20]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9559.86 Da        Isoelectric Point: 4.4929

>AT158598 WP_071625931.1 NZ_CP054052:c1389059-1388811 [Poseidonibacter lekithochrous]
MVVEKSRTNVYLDTNLKEQAKEIYKHYGLSLSEAVNMFLAQSVFNRGLPFEVKIPNDMTLETMKDIETGENYEDIRLEDL
NK

Download         Length: 249 bp

>AT158598 NZ_CP069692:3650567-3650941 [Escherichia coli H20]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References