158538

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 837369..837949 Replicon plasmid pPR13E01
Accession NZ_CP054032
Organism Rhizobium indicum strain JKLM 13E

Toxin (Protein)


Gene name vapC Uniprot ID A0A1B1CJ75
Locus tag FE844_RS27920 Protein ID WP_033182978.1
Coordinates 837566..837949 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F7XCL0
Locus tag FE844_RS27915 Protein ID WP_013851145.1
Coordinates 837369..837569 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE844_RS27890 832511..834955 - 2445 WP_138330933.1 caspase family protein -
FE844_RS27895 835413..835850 + 438 WP_138330932.1 curlin -
FE844_RS27900 835915..836313 + 399 WP_138331179.1 hypothetical protein -
FE844_RS27905 836479..836892 + 414 WP_173863057.1 curlin -
FE844_RS27910 836974..837234 + 261 WP_173863058.1 hypothetical protein -
FE844_RS27915 837369..837569 + 201 WP_013851145.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FE844_RS27920 837566..837949 + 384 WP_033182978.1 type II toxin-antitoxin system VapC family toxin Toxin
FE844_RS27925 838300..838673 + 374 Protein_800 multicopper oxidase domain-containing protein -
FE844_RS27930 838750..838959 + 210 WP_138330930.1 cold-shock protein -
FE844_RS27935 839160..839612 - 453 WP_138330929.1 DUF411 domain-containing protein -
FE844_RS27940 839837..840421 + 585 WP_138330928.1 cation diffusion facilitator family transporter -
FE844_RS27945 840473..841249 - 777 Protein_804 efflux RND transporter permease subunit -
FE844_RS27950 841235..841825 + 591 Protein_805 IS21-like element helper ATPase IstB -
FE844_RS27955 841981..842655 - 675 WP_138331178.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1207524 1207524


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14147.33 Da        Isoelectric Point: 9.1808

>T158538 WP_033182978.1 NZ_CP054032:837566-837949 [Rhizobium indicum]
VILADTSIWIDHFRHVDAELRTIIEDDRLLCHPAVVGELALGSLRDRGRVITFLAAQRQAFVATHDEVMTMIDRHGIFSM
GIGYTDAHLLASILLDRRAALWTRDKRLQAAAKKAGASLHKPANARN

Download         Length: 384 bp

>T158538 NZ_CP069666:c2367376-2367200 [Escherichia coli O89m:H9]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATAGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7096.22 Da        Isoelectric Point: 11.1107

>AT158538 WP_013851145.1 NZ_CP054032:837369-837569 [Rhizobium indicum]
MRSTINLDDTLMERAKSLTGTKETAALVRQALETLVRVESGKRLIALGGTMPDAEAAPRRRSAAAK

Download         Length: 201 bp

>AT158538 NZ_CP069666:c2367154-2366738 [Escherichia coli O89m:H9]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B1CJ75

Antitoxin

Source ID Structure
AlphaFold DB A0A7W6MID2

References