158535

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 563114..563904 Replicon plasmid pPR13E01
Accession NZ_CP054032
Organism Rhizobium indicum strain JKLM 13E

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag FE844_RS26575 Protein ID WP_138331138.1
Coordinates 563114..563611 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag FE844_RS26580 Protein ID WP_138331137.1
Coordinates 563608..563904 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE844_RS26555 558578..559327 + 750 WP_138331142.1 urea ABC transporter ATP-binding protein UrtD -
FE844_RS26560 559327..560022 + 696 WP_138331141.1 urea ABC transporter ATP-binding subunit UrtE -
FE844_RS26565 560051..561802 + 1752 WP_173863035.1 amidohydrolase -
FE844_RS26570 561814..562971 + 1158 WP_138331139.1 iron-containing alcohol dehydrogenase -
FE844_RS26575 563114..563611 - 498 WP_138331138.1 GNAT family N-acetyltransferase Toxin
FE844_RS26580 563608..563904 - 297 WP_138331137.1 DUF1778 domain-containing protein Antitoxin
FE844_RS26585 564253..564897 - 645 WP_138331203.1 nucleotidyltransferase family protein -
FE844_RS26590 565092..565799 - 708 WP_138331136.1 XdhC family protein -
FE844_RS26595 565799..566128 - 330 WP_138331135.1 XdhC family protein -
FE844_RS26600 566125..568488 - 2364 WP_138331134.1 glycoside hydrolase family 3 C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1207524 1207524


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-142)

Antitoxin

Vibrio phage ICP1, Orf50

(7-97)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17696.29 Da        Isoelectric Point: 8.0964

>T158535 WP_138331138.1 NZ_CP054032:c563611-563114 [Rhizobium indicum]
VTVSVPAPLADHHELAEFHSGVPELDDWLRLRARANQASGASRTFVVCEANRVIAYYALASGAVKQSEAPGRFRRNMPDP
IPVAVLGRLAIDKSYQGRGFGRALVRDAGLRLINAAEILGIRGVLVHAISGDARAFYEAVGFLPSPSDPMMLLVGLHDLN
NALTS

Download         Length: 498 bp

>T158535 NZ_CP069666:1761987-1762241 [Escherichia coli O89m:H9]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11111.65 Da        Isoelectric Point: 7.0157

>AT158535 WP_138331137.1 NZ_CP054032:c563904-563608 [Rhizobium indicum]
MPTSHTSKSKDASVPLNMRIKPATRNLIDRAAEMLGKTRTDFMLEASERRAEEVLLDQTIFTVSAEVYAEYLARLDAPTQ
PNERLKRTMSTKAPWDEA

Download         Length: 297 bp

>AT158535 NZ_CP069666:1761739-1761990 [Escherichia coli O89m:H9]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References