Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 573001..573596 Replicon chromosome
Accession NZ_CP054031
Organism Rhizobium indicum strain JKLM 13E

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FE844_RS02860 Protein ID WP_138328230.1
Coordinates 573001..573390 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FE844_RS02865 Protein ID WP_138328959.1
Coordinates 573387..573596 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE844_RS02840 568104..568724 - 621 WP_072638785.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
FE844_RS02845 568803..570092 - 1290 WP_138328231.1 dihydroorotase -
FE844_RS02850 570089..571045 - 957 WP_007626148.1 aspartate carbamoyltransferase catalytic subunit -
FE844_RS02855 571225..572883 + 1659 WP_028741374.1 acyl-CoA dehydrogenase family protein -
FE844_RS02860 573001..573390 - 390 WP_138328230.1 PIN domain nuclease Toxin
FE844_RS02865 573387..573596 - 210 WP_138328959.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FE844_RS02870 573741..576614 - 2874 WP_138328229.1 Rne/Rng family ribonuclease -
FE844_RS02875 577238..578494 + 1257 WP_011651401.1 N-acetylmuramoyl-L-alanine amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14642.92 Da        Isoelectric Point: 6.4892

>T158532 WP_138328230.1 NZ_CP054031:c573390-573001 [Rhizobium indicum]
VIVVDSSVWIAHMRGIESAAMRRLQNIEDPSDVIVGDLILLEVLQGARSERHAAIIEQSLRKFTIRPMLNDDLAVQAARN
YRLLRERDVTVRKTIDVIIGTFCIHEGHALLHDDRDFNPMAEHLGLRIA

Download         Length: 390 bp

>T158532 NZ_CP069666:819695-820102 [Escherichia coli O89m:H9]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7649.62 Da        Isoelectric Point: 5.8065

>AT158532 WP_138328959.1 NZ_CP054031:c573596-573387 [Rhizobium indicum]
MRTNIDIDDALLNAAMTATGLATKKATVEQALRSLVEKHSRRNAIANLAGIGWEGDLDEMRNDRPDEKR

Download         Length: 210 bp

>AT158532 NZ_CP069666:819448-819714 [Escherichia coli O89m:H9]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References