158520

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 951128..951934 Replicon chromosome
Accession NZ_CP054017
Organism Staphylococcus warneri strain FDAARGOS_754

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag FOC62_RS04675 Protein ID WP_002452099.1
Coordinates 951128..951307 (-) Length 60 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag FOC62_RS04680 Protein ID WP_002452098.1
Coordinates 951335..951934 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC62_RS04650 946219..946842 - 624 WP_002452104.1 response regulator transcription factor -
FOC62_RS04655 946863..947975 - 1113 WP_002452103.1 GAF domain-containing sensor histidine kinase -
FOC62_RS04660 948153..948983 + 831 WP_002452102.1 RluA family pseudouridine synthase -
FOC62_RS04665 949042..950427 - 1386 WP_002452101.1 class II fumarate hydratase -
FOC62_RS04670 950582..950974 - 393 WP_002452100.1 hypothetical protein -
FOC62_RS04675 951128..951307 - 180 WP_002452099.1 hypothetical protein Toxin
FOC62_RS04680 951335..951934 - 600 WP_002452098.1 glucosamine-6-phosphate isomerase Antitoxin
FOC62_RS04685 952115..952585 - 471 WP_002452097.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
FOC62_RS04690 952586..953716 - 1131 WP_002452096.1 tRNA epoxyqueuosine(34) reductase QueG -
FOC62_RS04695 953974..954696 - 723 WP_002452095.1 amino acid ABC transporter ATP-binding protein -
FOC62_RS04700 954689..956149 - 1461 WP_002452094.1 ABC transporter substrate-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(125-195)


Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6957.29 Da        Isoelectric Point: 3.8537

>T158520 WP_002452099.1 NZ_CP054017:c951307-951128 [Staphylococcus warneri]
MTQNKDSRTNYHEEENAMVTDLDDLKDLGKEMEQISEENDEDKLNQSHDSELRSDLDQE

Download         Length: 180 bp

>T158520 NZ_CP069657:c3777905-3777507 [Escherichia coli O89m:H10]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22575.46 Da        Isoelectric Point: 4.8492

>AT158520 WP_002452098.1 NZ_CP054017:c951934-951335 [Staphylococcus warneri]
MAMNFKVFEDKQRVAEYTADILRKQFNNNPMTIAGVHLTKDHAPVLDELKKNVDLHAVDFSQINILDYDENQSYYEALGV
PQSQIYSLSYNQDANDFISDKIKTKENKGKLVLQVVSIDESGNLDVSVRQGLLEAREIFLVVTGSNKREVVEKLYNENGK
SNFEPADLKAHRMVNVILDKEAAAGLPEDVKEYFTARFA

Download         Length: 600 bp

>AT158520 NZ_CP069657:c3778201-3777908 [Escherichia coli O89m:H10]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References