Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 6059674..6060338 Replicon chromosome
Accession NZ_CP053985
Organism Achromobacter pestifer strain FDAARGOS_790

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FOC84_RS28640 Protein ID WP_173148243.1
Coordinates 6059674..6060090 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FOC84_RS28645 Protein ID WP_173148245.1
Coordinates 6060087..6060338 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC84_RS28625 6055368..6055967 - 600 WP_173148239.1 C40 family peptidase -
FOC84_RS28630 6056282..6057778 + 1497 WP_173150470.1 AMP nucleosidase -
FOC84_RS28635 6057913..6059472 + 1560 WP_173148241.1 amino acid permease -
FOC84_RS28640 6059674..6060090 - 417 WP_173148243.1 type II toxin-antitoxin system VapC family toxin Toxin
FOC84_RS28645 6060087..6060338 - 252 WP_173148245.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FOC84_RS28650 6060614..6061546 - 933 WP_173148247.1 YicC family protein -
FOC84_RS28655 6061747..6062463 + 717 WP_173150471.1 ribonuclease PH -
FOC84_RS28660 6062529..6063905 - 1377 WP_173148249.1 MmgE/PrpD family protein -
FOC84_RS28665 6063922..6065082 - 1161 WP_173148251.1 acyl-CoA/acyl-ACP dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15649.03 Da        Isoelectric Point: 6.4730

>T158374 WP_173148243.1 NZ_CP053985:c6060090-6059674 [Achromobacter pestifer]
MSYLVDTNVLSELRRKQPDGNVVRWLQKRPPTTLFLSALTLGELRKGIEMMPEGERKRSYLDWLEVELPRFFSGRVLTID
EPVVDCWGRLVAKAGRTLPAIDSLLAATAMTHGLTLVTRNEQDFQHSGLDVINPWEGT

Download         Length: 417 bp

>T158374 NZ_CP069630:c739442-739188 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9004.10 Da        Isoelectric Point: 5.8065

>AT158374 WP_173148245.1 NZ_CP053985:c6060338-6060087 [Achromobacter pestifer]
MQAWQMQEAKSRLSEVVKAAGSQGPQEITVHGRSVAVVLSRSDFDKLSGTGESLVAFMRRSPLAGDEDLDFPRDASPTRK
DGL

Download         Length: 252 bp

>AT158374 NZ_CP069630:c739690-739439 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References