Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 2206276..2207433 Replicon chromosome
Accession NZ_CP053985
Organism Achromobacter pestifer strain FDAARGOS_790

Toxin (Protein)


Gene name VbhT Uniprot ID -
Locus tag FOC84_RS10690 Protein ID WP_173144399.1
Coordinates 2206276..2207190 (-) Length 305 a.a.

Antitoxin (Protein)


Gene name VbhA Uniprot ID -
Locus tag FOC84_RS10695 Protein ID WP_088153977.1
Coordinates 2207227..2207433 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC84_RS10675 2202005..2202463 + 459 WP_173144397.1 Lrp/AsnC family transcriptional regulator -
FOC84_RS10680 2202523..2203404 - 882 WP_173150067.1 sensor domain-containing diguanylate cyclase -
FOC84_RS10685 2204636..2204917 - 282 WP_173144398.1 hypothetical protein -
FOC84_RS10690 2206276..2207190 - 915 WP_173144399.1 Fic/DOC family protein Toxin
FOC84_RS10695 2207227..2207433 - 207 WP_088153977.1 antitoxin VbhA family protein Antitoxin
FOC84_RS10700 2207881..2208303 - 423 WP_173144400.1 hypothetical protein -
FOC84_RS10705 2208326..2208595 - 270 WP_173144401.1 hypothetical protein -
FOC84_RS10710 2208615..2208953 - 339 WP_173144402.1 H-NS histone family protein -
FOC84_RS10715 2209008..2209304 - 297 WP_173144403.1 hypothetical protein -
FOC84_RS10720 2209403..2210527 - 1125 WP_173144404.1 ParB/RepB/Spo0J family partition protein -
FOC84_RS10725 2210517..2211497 + 981 WP_173144405.1 DUF1173 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2151585..2212892 61307


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(56-151)

Antitoxin

Antitoxin VbhA-like

(6-57)


Sequences

Toxin        


Download         Length: 305 a.a.        Molecular weight: 33891.14 Da        Isoelectric Point: 5.7863

>T158372 WP_173144399.1 NZ_CP053985:c2207190-2206276 [Achromobacter pestifer]
MAKYPVRTSDPYLDEHSGLLRNRLGITDQAELDRVEATFGLVRAYELVEKPVAGNFDLAHLQAIHKRLFGDVYDWAGEIR
TVDISKGQTRFANFQQIESYAPEITRPLQREQLLRGLNIDTFSERAGHYLGELNVLHPFREGNGRATREFVGQLARGAGY
AVDWSGIERTEMIHASIEAYEGSSKRLAGLIRASLVDIDKERALDLAMAVSGGKVEISPAEPGHAYEGAVVGSTERYVVQ
SLGDEMVLHTRQALLNAEMLVPGQIVNIRYPHGGVGLVEGEGTPQIDKPLQHDHERKRDRDLER

Download         Length: 915 bp

>T158372 NZ_CP069630:c398025-397923 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7750.88 Da        Isoelectric Point: 5.8573

>AT158372 WP_088153977.1 NZ_CP053985:c2207433-2207227 [Achromobacter pestifer]
MIDCKEQRERERAIHIAVANQRLEGLEPDAITIAELGRVAKGELTVEEVLRNLRRRIDAGEFQQVPAK

Download         Length: 207 bp

>AT158372 NZ_CP069630:397885-398153 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References