Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 448686..449125 Replicon chromosome
Accession NZ_CP053923
Organism Defluviicoccus vanus strain Ben 114

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HQ394_RS02045 Protein ID WP_190261807.1
Coordinates 448934..449125 (+) Length 64 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HQ394_RS02040 Protein ID WP_190261806.1
Coordinates 448686..448937 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ394_RS02020 444371..445099 + 729 WP_190261802.1 hypothetical protein -
HQ394_RS02025 445326..446606 - 1281 WP_190261803.1 site-specific integrase -
HQ394_RS02030 446891..447265 + 375 WP_190261804.1 hypothetical protein -
HQ394_RS02035 447270..448358 + 1089 WP_190261805.1 relaxase/mobilization nuclease domain-containing protein -
HQ394_RS02040 448686..448937 + 252 WP_190261806.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HQ394_RS02045 448934..449125 + 192 WP_190261807.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HQ394_RS02050 449208..450569 - 1362 WP_190260069.1 IS1182 family transposase -
HQ394_RS02055 450652..450798 + 147 WP_190263074.1 type II toxin-antitoxin system RelE/ParE family toxin -
HQ394_RS02060 450862..451986 - 1125 WP_190261808.1 DUF3800 domain-containing protein -
HQ394_RS02065 452006..452251 - 246 WP_190261809.1 type II toxin-antitoxin system ParD family antitoxin -
HQ394_RS02070 453225..453482 + 258 WP_190261810.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
HQ394_RS02075 453482..453775 + 294 WP_190261811.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-49)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 6840.70 Da        Isoelectric Point: 5.4821

>T158283 WP_190261807.1 NZ_CP053923:448934-449125 [Defluviicoccus vanus]
MSYRTTKRADQDIIDIYVHGATAFGVDQAERYHEGMVSVFELLAENPHLAACRTCVSGVAGPA

Download         Length: 192 bp

>T158283 NZ_CP069604:c981700-981395 [Dickeya dianthicola]
ATGCAATTCATTGTTTACCAATACAAACGAGCCAGTCACTACAAAATGTTTGTCGATGTGCAAAGCGATATTGTCGAGAC
ACCAAAGCGGCGTATGGTCATTCCGCTTATAGAATCGCATCACCTGTCTGAGAAGGTGAATAAAACGCTGTTCCCTCAGA
TCCGGATCGACGGCGAAGATTATCGGCTGATGACGACTGAACTATCGAGCGTTCCCGTTGAAGTTATTGGTGAAGAGCTC
GCGGAGCTTGGCGACTATGCGGATGAGATCAAGGATGCTATTAATCTTATGTTTTGGGGGATTTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9179.29 Da        Isoelectric Point: 5.1351

>AT158283 WP_190261806.1 NZ_CP053923:448686-448937 [Defluviicoccus vanus]
MATMNVSLPDPMKDWVEAQARSGRYSNASDYVRDLIRRDQERAGKLAELQALLTEGLESGVSDRTIDEVLKAAREQAKTA
RGA

Download         Length: 252 bp

>AT158283 NZ_CP069604:c981921-981703 [Dickeya dianthicola]
ATGAAACACCGCGTCAGCGTTACCGTGGACAAAGACAACTATCAGATTCTGAGTGCTGCCGGAGTCAATATTTCTGGTCT
GGTGAATGATGCCATTGGCAAAGAAGCCCGCCGTATCAAGGCTGAGCAGTGGAAGAAGGAAAACCGCGAAGGGATGGAAG
AAGTCGCCCGATTTATCGCACAAAATGGCTCGTTTGCTGATGAAAACAGGAACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References