Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 4227788..4228373 Replicon chromosome
Accession NZ_CP053896
Organism Providencia rettgeri strain YPR31

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HRD55_RS19480 Protein ID WP_110591061.1
Coordinates 4227788..4228105 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HRD55_RS19485 Protein ID WP_172767478.1
Coordinates 4228086..4228373 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRD55_RS19450 4223491..4223742 - 252 WP_172767476.1 DUF1471 domain-containing protein -
HRD55_RS19455 4224013..4224351 + 339 WP_004905864.1 GIY-YIG nuclease family protein -
HRD55_RS19460 4224324..4224827 - 504 WP_172767477.1 N-acetyltransferase -
HRD55_RS19465 4224821..4225345 - 525 WP_004905868.1 SCP2 domain-containing protein -
HRD55_RS19470 4225860..4226855 + 996 WP_094961644.1 U32 family peptidase -
HRD55_RS19475 4226873..4227748 + 876 WP_164565609.1 U32 family peptidase -
HRD55_RS19480 4227788..4228105 - 318 WP_110591061.1 type II toxin-antitoxin system YafQ family toxin Toxin
HRD55_RS19485 4228086..4228373 - 288 WP_172767478.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HRD55_RS19490 4228504..4229658 - 1155 WP_004905877.1 ABC transporter permease -
HRD55_RS19495 4229658..4230803 - 1146 WP_004905879.1 ABC transporter permease -
HRD55_RS19500 4230815..4231786 - 972 WP_004905881.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(14-104)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-87)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 12206.90 Da        Isoelectric Point: 8.4953

>T158254 WP_110591061.1 NZ_CP053896:c4228105-4227788 [Providencia rettgeri]
MTQKPSNKRAKQPRQVAYTPTFKESWERYNRAGRRDMNAAVLVMEILFSQKIIPKEYLDHELEGHEWQGARELHIGGDFL
LVYRLSDKGNLITFVDIGSHSELFG

Download         Length: 318 bp

>T158254 NZ_CP069601:1578334-1578648 [Dickeya dianthicola]
ATGCAATTCACCGTATACGGTAATACTGGGAAAAGCGTCGTTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
GCAGTTAAATCGCCGGATAGTGATCCCGTTGCTCCCGGTTGAAAAGTACCCGGCAGGCCGCCGGCCGGATCGCCTAGTCC
CTGTCGTCAGGCTGACGGACGGTAAAGAATACGCCGTAATGGCGCACGAGCTGGCAAGTATCCCTGTGCAGGCTCTGGGG
GCGGTGTTCTGTGATGCGTCGCAGTACCGTACTCAGGTAAAGGCCGCAATAGATTTCCTCATTGACGGTATTTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10789.47 Da        Isoelectric Point: 5.1969

>AT158254 WP_172767478.1 NZ_CP053896:c4228373-4228086 [Providencia rettgeri]
MSTLLKTTDVRSRIDEQLKAEATSVLQDCGLTISAAIRLFLEQVVQEQRVPFEIKRKQPSLKTTLALKEAKAIEQYYDSI
NEMMVELSKVDSEAK

Download         Length: 288 bp

>AT158254 NZ_CP069601:1578095-1578331 [Dickeya dianthicola]
ATGACCGCGAAACAACGCAACACGCAGAGCGTGACCATGACGGTAGAGCGTGCCTTACTGCTCCGGGCGCGTGAAGCGGG
TATTAACCTGAGTGCCACCCTGACAACCGCCCTGGATGCAGAGCTTCGCCGTTATGAGGCGAAAAAATGGCAGGAAGAGA
ACCGGGAAGCCATCGACGCATTAAACCGTTTTCATGATGAAAACGGCTGTTTCAGCGATGAATACCGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References