158229

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) itaRT/DUF1778(antitoxin)
Location 4253550..4254387 Replicon chromosome
Accession NZ_CP053883
Organism Aeromonas hydrophila strain 4960

Toxin (Protein)


Gene name itaT Uniprot ID -
Locus tag HQ397_RS19550 Protein ID WP_252376307.1
Coordinates 4253836..4254387 (+) Length 184 a.a.

Antitoxin (Protein)


Gene name itaR Uniprot ID -
Locus tag HQ397_RS19545 Protein ID WP_252376306.1
Coordinates 4253550..4253855 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ397_RS19540 (HQ397_19470) 4251233..4253275 + 2043 WP_252376305.1 exodeoxyribonuclease V subunit alpha -
HQ397_RS19545 (HQ397_19475) 4253550..4253855 + 306 WP_252376306.1 DUF1778 domain-containing protein Antitoxin
HQ397_RS19550 (HQ397_19480) 4253836..4254387 + 552 WP_252376307.1 hypothetical protein Toxin
HQ397_RS19555 (HQ397_19485) 4254643..4255368 + 726 WP_252376308.1 hypothetical protein -
HQ397_RS19560 (HQ397_19490) 4255502..4255899 - 398 Protein_3791 VOC family protein -
HQ397_RS19565 (HQ397_19495) 4255975..4256895 + 921 WP_252376309.1 AraC family transcriptional regulator -
HQ397_RS19570 (HQ397_19500) 4257084..4258085 + 1002 WP_252377632.1 sensor domain-containing diguanylate cyclase -
HQ397_RS19575 (HQ397_19505) 4258244..4258663 + 420 WP_011707651.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(17-94)


Sequences

Toxin        


Download         Length: 184 a.a.        Molecular weight: 20408.46 Da        Isoelectric Point: 6.2397

>T158229 WP_252376307.1 NZ_CP053883:4253836-4254387 [Aeromonas hydrophila]
MEEQKNEDVTSNVLTICKYDADITYPGQKKFDCGNKVINDYVAKSLKSNVRNGDAYSQALIDVKTGDFFGFFSCTGYSLA
RTRLAGVFEKSLPSEVFVIRLVMLGVSIDKQKKEYGLDLMQSFFEHALKVHETMPIKGVFLDADPEAVNFYTRLGFIPLP
EPSHGGVTPMFLKIQDLVKATAS

Download         Length: 552 bp

>T158229 NZ_CP069599:c988564-987908 [Dickeya dianthicola]
GTGGCCTATGACTACAGCGCCAATCTCAACCCGGAAAAGGCCCTTATCTGGCGCATTGTCCACCGGGACAACATCCCGTG
GATACTGGACAACGGTCTACACTGCGGCAACAGCCCGGTGCAGGCTGCAAACTGGATCAATATTGGTAACCCGGAGCTTA
TCAACAGACGCGCCGGGCACCCGGTGCCTGCCGGGGCGGGTGGTACGCTGCATGACTATGTGCCGTTTTACTTTACCCCC
TTCTCACCGATGCTGATGAATATCCACAGTGGGCGCGGCGGCATTAAGCAACGTCCCAACGAAGAAATCGTCATTCTGGT
CAGCAGCCTGCGACATGTGGCGATACAAAACGTCCCCTTCGTGTTTACCGACAGCCACGCCTACTATAATCTGGCGAATT
ACTATACCGATCTAAACAATCTGCACCGGATCGACTGGCCCATTTTACAGGCGCGGGATTTCCGTCGCGATCAGGACGAT
CTTGCCAAGTTTGAACGCTATCAGGCCGAGGCGTTAATCTGGCAGCACTGCCCCATCACGCTGCTGGTCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGAGCAATGGCTGTCGCAACGCAATCTGACAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11240.93 Da        Isoelectric Point: 10.5523

>AT158229 WP_252376306.1 NZ_CP053883:4253550-4253855 [Aeromonas hydrophila]
MSSLLMDSSSRKQKDARVDLKTSSDLKDLLRQAASIAGVDLSAFILTAAFERAEAVLENQKRRELSEESWKLLNAVMAEP
ASPTLALHALMRRKRNGRAKE

Download         Length: 306 bp

>AT158229 NZ_CP069599:c987911-986844 [Dickeya dianthicola]
ATGATGACATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTGAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTCCCCGATAATATGAAAGCCTATGCACTCGCCTGTAAACAAAAGC
AGGTGACGACTGGCAAAATGTTTATCACTGAAACCGACGAGCTGATGGGGCCACGCTGGATCGTCAACTTCCCTACCAAG
CAGCACTGGCGCGCCGACTCTCGCATGGAGTGGATTGAAGACGGCTTACAGGACTTACGTCGCTTTTTGATCGAAGAGAA
AGTGCAGTCCATCGCCATTCCTCCGCTGGGGGCGGGAAACGGCGGCCTGAACTGGTCGGACGTGCAGGCGCGGATTGAAT
CTGCGCTGGGCGACCTTCAGGACACGGAAATCCTGATTTATGAGCCTACCGAAAAATACCAAAACGTCGCCAAGAGTACC
GGCGTAAAAAAGCTCACCCCCGCCAGAGCGATGATCGCTGAACTGGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCCATTGAACAGCACCAGCAGGAGGACGTGCTAAAACTGC
GGTTTGAGGCACACAATTATGGCCCGTATGCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAG
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTGGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACATTAATCTCTG
GCTGAATAACGAGGCCAAAGCGTGGCTACCGGCGCTTGAGCAGGTCAGCCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCGACCGTTGACTGGCTGCTGACCCGAGGAGAGTGCCAGCCCACGCTGGATTCCGTGAAAGAGGGG
CTACACCAGTGGCCTGCCGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTCTTTGACGACAAAAATCTGCAATTTGCCAT
AAACCGTGTCATGGAGTTCCATTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References