158213

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2044696..2044841 Replicon chromosome
Accession NZ_CP053875
Organism Klebsiella pneumoniae strain KPN142

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2044732..2044834 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2044696..2044841 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPY03_RS10090 (HPY03_10090) 2039826..2041886 + 2061 WP_004151449.1 oligopeptidase B -
HPY03_RS10095 (HPY03_10095) 2041890..2042549 - 660 WP_002911407.1 exodeoxyribonuclease X -
HPY03_RS10100 (HPY03_10100) 2042628..2042858 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HPY03_RS10105 (HPY03_10105) 2042971..2043345 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HPY03_RS10110 (HPY03_10110) 2043349..2044218 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
HPY03_RS10115 (HPY03_10115) 2044235..2044573 + 339 WP_002911404.1 YebY family protein -
- 2044696..2044841 - 146 - - Antitoxin
- 2044732..2044834 + 103 - - Toxin
HPY03_RS10120 (HPY03_10120) 2045209..2045352 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HPY03_RS10125 (HPY03_10125) 2045457..2046425 - 969 WP_004151446.1 VirK/YbjX family protein -
HPY03_RS10130 (HPY03_10130) 2046582..2047235 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HPY03_RS10135 (HPY03_10135) 2047232..2047423 - 192 WP_002911395.1 YebW family protein -
HPY03_RS10140 (HPY03_10140) 2047521..2047760 - 240 WP_002911393.1 YebV family protein -
HPY03_RS10145 (HPY03_10145) 2047876..2049309 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T158213 NZ_CP053875:2044732-2044834 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT158213 NZ_CP053875:c2044841-2044696 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References