Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029001..2029146 Replicon chromosome
Accession NZ_CP053862
Organism Klebsiella pneumoniae strain KP-Zhen

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029037..2029139 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029001..2029146 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GWF98_RS09630 2024131..2026191 + 2061 WP_004151449.1 oligopeptidase B -
GWF98_RS09635 2026195..2026854 - 660 WP_002911407.1 exodeoxyribonuclease X -
GWF98_RS09640 2026933..2027163 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GWF98_RS09645 2027276..2027650 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GWF98_RS09650 2027654..2028523 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
GWF98_RS09655 2028540..2028878 + 339 WP_002911404.1 YebY family protein -
- 2029001..2029146 - 146 - - Antitoxin
- 2029037..2029139 + 103 - - Toxin
GWF98_RS09660 2029514..2029657 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GWF98_RS09665 2029762..2030730 - 969 WP_014907334.1 VirK/YbjX family protein -
GWF98_RS09670 2030887..2031540 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
GWF98_RS09675 2031537..2031728 - 192 WP_002911395.1 YebW family protein -
GWF98_RS09680 2031826..2032065 - 240 WP_002911393.1 YebV family protein -
GWF98_RS09685 2032181..2033614 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T158185 NZ_CP053862:2029037-2029139 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT158185 NZ_CP053862:c2029146-2029001 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References