Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 239549..240129 Replicon plasmid pR76
Accession NZ_CP053858
Organism Rhizobium pusense strain 76

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HQN82_RS24250 Protein ID WP_173616195.1
Coordinates 239549..239932 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A5D9CLR1
Locus tag HQN82_RS24255 Protein ID WP_006699143.1
Coordinates 239929..240129 (-) Length 67 a.a.

Genomic Context

HQN82_RS24230HQN82_RS24235HQN82_RS24240HQN82_RS24245HQN82_RS24265HQN82_RS24250HQN82_RS24255HQN82_RS24260
Location: 235459..237171 (1713 bp)
Type: Others
Protein ID: WP_173616192.1
Location: 237183..237968 (786 bp)
Type: Others
Protein ID: WP_173616193.1
Location: 237972..238823 (852 bp)
Type: Others
Protein ID: WP_173616194.1
Location: 239185..239460 (276 bp)
Type: Others
Protein ID: WP_173616403.1
Location: 242875..243981 (1107 bp)
Type: Others
Protein ID: WP_173616196.1
Location: 239549..239932 (384 bp)
Type: Toxin
Protein ID: WP_173616195.1
Location: 239929..240129 (201 bp)
Type: Antitoxin
Protein ID: WP_006699143.1
Location: 240310..242667 (2358 bp)
Type: Others
Protein ID: Protein_227
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HQN82_RS24230235459..237171+1713WP_173616192.1ABC transporter ATP-binding protein-
HQN82_RS24235237183..237968+786WP_173616193.1hydroxypyruvate isomerase-
HQN82_RS24240237972..238823+852WP_173616194.12-hydroxy-3-oxopropionate reductase-
HQN82_RS24245239185..239460+276WP_173616403.1hypothetical protein-
HQN82_RS24250239549..239932-384WP_173616195.1type II toxin-antitoxin system VapC family toxinToxin
HQN82_RS24255239929..240129-201WP_006699143.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
HQN82_RS24260240310..242667-2358Protein_227hypothetical protein-
HQN82_RS24265242875..243981+1107WP_173616196.1Fic family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-htpB / htpB1..486984486984


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14090.29 Da        Isoelectric Point: 7.1290

>T158181 WP_173616195.1 NZ_CP053858:c239932-239549 [Rhizobium pusense]
VILVDSSIWIDHFRHVNPELVKIIGDDQLLCHPFVVGELALGSLRERDAVLAFLTAQREAVVATHAEVMTVIDRHSIFSM
GIGYTDAHLLTSTLLDRRSSLWTRDKRLAAAARKVGAALYPSPHIPQ

Download         Length: 384 bp

>T158181 NZ_CP069594:c1731559-1731377 [Pseudomonas sp. Y39-6]
GTGGATAGCCGATATTTAATAGGCCATATCGTCGCCGACGGCTGGTATCTGGTGCGCGTCAGAGGTAGCCATCACCCCTT
CAAGCACCCGACGAAACCGGGGCTGGTGACAATTCCTCATCCGAAGAAGGACTTGTTGGACAAGACCGCCAAAAGCATGT
TGAAACAGGCACTGCTGAGTTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7168.28 Da        Isoelectric Point: 10.7407

>AT158181 WP_006699143.1 NZ_CP053858:c240129-239929 [Rhizobium pusense]
MRSTINLDDSLMERAKSLTGTKETAALVRQALETLVRVESGKRLIALGGTMPEAEAAPRRRSEVGK

Download         Length: 201 bp

>AT158181 NZ_CP069594:c1731354-1730944 [Pseudomonas sp. Y39-6]
GTGCTGTACCCCATCGCAATTTCTACTGGTGACGAAGACCATGCCTGGGGCGTGGAAGTCCCGGACATTCCTGGTTGCTA
CTCCGCCGGTGACGACTTGGATGACGCCATGGCCATGGCCCGTGAAGCGATTGAAGGCCACTTCGAAATTCTCGCCGAAG
ACGGTGCGCCGATTCCCAGCGCGCAGAAAGTCACCCTGCATGCAGCCAACCCCAAGTACGCCGGTTGCATGTGGGCAGTG
GTGGACATCGATGTCACCAAATACCTGGGCAAGGCGCAGAAACTCAACATCACCCTGCCAGGCTATTTGCTCAATCGTAT
CGATGAATACGTACTGCACCATCCCGAGGAAAAAAGCCGTTCGGGGTTCCTCGCGTCCGCAGCGCTCAAGGTGCTGCAAC
AGGATCGATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5D9CLR1

References