Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 444049..444593 Replicon chromosome
Accession NZ_CP053856
Organism Rhizobium pusense strain 76

Toxin (Protein)


Gene name parE Uniprot ID U4PRC3
Locus tag HQN82_RS02125 Protein ID WP_004440407.1
Coordinates 444303..444593 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HQN82_RS02120 Protein ID WP_107341193.1
Coordinates 444049..444300 (+) Length 84 a.a.

Genomic Context

HQN82_RS02100HQN82_RS02105HQN82_RS02115HQN82_RS02120HQN82_RS02125HQN82_RS02140HQN82_RS02145HQN82_RS02095HQN82_RS02110HQN82_RS02130HQN82_RS02135
Location: 440051..440731 (681 bp)
Type: Others
Protein ID: WP_004440402.1
Location: 440772..441233 (462 bp)
Type: Others
Protein ID: WP_112766665.1
Location: 442530..443675 (1146 bp)
Type: Others
Protein ID: WP_004440405.1
Location: 444049..444300 (252 bp)
Type: Antitoxin
Protein ID: WP_107341193.1
Location: 444303..444593 (291 bp)
Type: Toxin
Protein ID: WP_004440407.1
Location: 446434..446961 (528 bp)
Type: Others
Protein ID: WP_006699987.1
Location: 447090..447770 (681 bp)
Type: Others
Protein ID: WP_173614487.1
Location: 439147..439836 (690 bp)
Type: Others
Protein ID: WP_003520496.1
Location: 441193..442293 (1101 bp)
Type: Others
Protein ID: WP_045532570.1
Location: 444625..445236 (612 bp)
Type: Others
Protein ID: WP_112766511.1
Location: 445233..446336 (1104 bp)
Type: Others
Protein ID: WP_112766510.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HQN82_RS02095439147..439836-690WP_003520496.1HAD family hydrolase-
HQN82_RS02100440051..440731+681WP_004440402.1GntR family transcriptional regulator-
HQN82_RS02105440772..441233+462WP_112766665.1DUF1284 domain-containing protein-
HQN82_RS02110441193..442293-1101WP_045532570.1hypothetical protein-
HQN82_RS02115442530..443675+1146WP_004440405.1site-specific DNA-methyltransferase-
HQN82_RS02120444049..444300+252WP_107341193.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
HQN82_RS02125444303..444593+291WP_004440407.1type II toxin-antitoxin system RelE/ParE family toxinToxin
HQN82_RS02130444625..445236-612WP_112766511.1HAD family phosphatase-
HQN82_RS02135445233..446336-1104WP_112766510.1A/G-specific adenine glycosylase-
HQN82_RS02140446434..446961+528WP_006699987.1DUF721 domain-containing protein-
HQN82_RS02145447090..447770+681WP_173614487.1DsbA family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(8-62)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11253.77 Da        Isoelectric Point: 6.6456

>T158178 WP_004440407.1 NZ_CP053856:444303-444593 [Rhizobium pusense]
MGFRLSLPAEEDVIRIAQEGIDLFGPQQARKYHRELFAIFDLISRNPRIARERNELSPSVRIHPFRAHLVVYRVEADDDV
LIVRVRHGHEDWGNEP

Download         Length: 291 bp

>T158178 NZ_CP069594:c684936-684646 [Pseudomonas sp. Y39-6]
ATGAGCGAATCCTTTACCCGTTTCGATGCCGCAAAATACCTTAAGACTCCTTTTGAGATGGCCGCCTATCTGGATGCTTG
CTTTGAAGAAGATGCTGGCGACGGTCTGTTGATTCGCACAGCGTTGAACGATATCGCTCGCGCCCAAGGCATGACCCAAG
TCGCTCGCGACGCCGGCCTAGGACGAGAAAGTTTGTACAAAGCCCTCTCCAGCACTGGCAATCCCGAGTTCGCGACTATC
ATGAAGGTCATGAGAGCACTGGGGCTCAAACTTCACGCCACCGCGCTCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9300.50 Da        Isoelectric Point: 7.0134

>AT158178 WP_107341193.1 NZ_CP053856:444049-444300 [Rhizobium pusense]
MVTMNISLPGQMKEWVEAQSKTGRYSNASDYVRDLIRKDQERSEKIAAMQGLVDEGLQAPSGHRSEDALFAEAEARSMKR
KIG

Download         Length: 252 bp

>AT158178 NZ_CP069594:c685242-684940 [Pseudomonas sp. Y39-6]
ATGATTGAGTTCGAAGAATCCGTTGAGTTTGTCAAATGGCTCGAAGCAATGCGCGATCCGCTCGCAAAAGTACGCATTGT
GACAAGGCTGCGCATGGCGCAAGCAGGAAACTTCGGCGACTGTGAGGCTGTAGGAGAGGGCGTTTGCGAAATGCGAATCC
ACCAAGGCCCCGGGTATCGGGTTTACTTCACTCTCCGAGACAAGGTGGTTTATCTGCTGCTGATGGGCGGCGACAAATCA
ACACAAAGCCGAGACATCCAGCGTGCAATACACATGGCAAAAAATCTTGGCCGCAAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBU4PRC3

Antitoxin

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Source
ID
Structure
No matching records found

References