Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 1573313..1573815 Replicon chromosome
Accession NZ_CP053845
Organism Campylobacter sp. CCUG 57310

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CORI_RS07885 Protein ID WP_173031517.1
Coordinates 1573313..1573588 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag CORI_RS07890 Protein ID WP_173031518.1
Coordinates 1573585..1573815 (-) Length 77 a.a.

Genomic Context

CORI_RS07865CORI_RS07870CORI_RS07875CORI_RS07880CORI_RS07885CORI_RS07890CORI_RS07895CORI_RS07900CORI_RS07905CORI_RS07910CORI_RS07915CORI_RS07920CORI_RS07925CORI_RS07930CORI_RS07935
Location: 1569643..1569915 (273 bp)
Type: Others
Protein ID: WP_173031513.1
Location: 1569912..1572101 (2190 bp)
Type: Others
Protein ID: WP_173031514.1
Location: 1572145..1572408 (264 bp)
Type: Others
Protein ID: WP_173031515.1
Location: 1572411..1572956 (546 bp)
Type: Others
Protein ID: WP_173031516.1
Location: 1573313..1573588 (276 bp)
Type: Toxin
Protein ID: WP_173031517.1
Location: 1573585..1573815 (231 bp)
Type: Antitoxin
Protein ID: WP_173031518.1
Location: 1574172..1574399 (228 bp)
Type: Others
Protein ID: WP_173031519.1
Location: 1574451..1574645 (195 bp)
Type: Others
Protein ID: WP_173031520.1
Location: 1574687..1574860 (174 bp)
Type: Others
Protein ID: WP_173031521.1
Location: 1574891..1575334 (444 bp)
Type: Others
Protein ID: WP_173031522.1
Location: 1575454..1576632 (1179 bp)
Type: Others
Protein ID: WP_173031523.1
Location: 1576690..1577343 (654 bp)
Type: Others
Protein ID: WP_173031524.1
Location: 1577376..1577606 (231 bp)
Type: Others
Protein ID: WP_173031525.1
Location: 1577616..1578158 (543 bp)
Type: Others
Protein ID: WP_173031526.1
Location: 1578319..1578582 (264 bp)
Type: Others
Protein ID: WP_173031527.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CORI_RS078651569643..1569915-273WP_173031513.1CRISPR-associated endonuclease Cas2-
CORI_RS078701569912..1572101-2190WP_173031514.1CRISPR-associated endonuclease Cas1-
CORI_RS078751572145..1572408-264WP_173031515.1CRISPR system precrRNA processing endoribonuclease RAMP protein Cas6-
CORI_RS078801572411..1572956-546WP_173031516.1hypothetical protein-
CORI_RS078851573313..1573588-276WP_173031517.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CORI_RS078901573585..1573815-231WP_173031518.1ribbon-helix-helix domain-containing proteinAntitoxin
CORI_RS078951574172..1574399-228WP_173031519.1hypothetical protein-
CORI_RS079001574451..1574645-195WP_173031520.1hypothetical protein-
CORI_RS079051574687..1574860-174WP_173031521.1hypothetical protein-
CORI_RS079101574891..1575334-444WP_173031522.1hypothetical protein-
CORI_RS079151575454..1576632-1179WP_173031523.1LysM peptidoglycan-binding domain-containing protein-
CORI_RS079201576690..1577343-654WP_173031524.1hypothetical protein-
CORI_RS079251577376..1577606-231WP_173031525.1hypothetical protein-
CORI_RS079301577616..1578158-543WP_173031526.1hypothetical protein-
CORI_RS079351578319..1578582-264WP_173031527.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-84)

Antitoxin

Protein of unknown function DUF6290

(2-72)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10342.10 Da        Isoelectric Point: 10.0088

>T158105 WP_173031517.1 NZ_CP053845:c1573588-1573313 [Campylobacter sp. CCUG 57310]
MKVNFSKNALKELKKLDNSVSIKILKKLKEIEGLDNPRDEGKPLIGNLSGLWRYRVGGYRIICKIKDHELIVLVLGVRNR
SDAYDGEFDGV

Download         Length: 276 bp

>T158105 NZ_CP069571:3415763-3417085 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8931.25 Da        Isoelectric Point: 4.8660

>AT158105 WP_173031518.1 NZ_CP053845:c1573815-1573585 [Campylobacter sp. CCUG 57310]
MQISVRLDKDIGTKLERLAKDTKRTKSFYVQEAIKRFLEDMNDYIDAMEELKKIESDSNPQFYTLDEVAKELGVKI

Download         Length: 231 bp

>AT158105 NZ_CP069571:3415497-3415763 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References