Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5183735..5183880 Replicon chromosome
Accession NZ_CP053771
Organism Klebsiella pneumoniae strain BP3636

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5183771..5183873 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5183735..5183880 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBJ33_RS24875 5178865..5180925 + 2061 WP_004151449.1 oligopeptidase B -
HBJ33_RS24880 5180929..5181588 - 660 WP_043906809.1 exodeoxyribonuclease X -
HBJ33_RS24885 5181667..5181897 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HBJ33_RS24890 5182010..5182384 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HBJ33_RS24895 5182388..5183257 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HBJ33_RS24900 5183274..5183612 + 339 WP_002911404.1 YebY family protein -
- 5183735..5183880 - 146 - - Antitoxin
- 5183771..5183873 + 103 - - Toxin
HBJ33_RS24905 5184249..5184392 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HBJ33_RS24910 5184497..5185465 - 969 WP_004151446.1 VirK/YbjX family protein -
HBJ33_RS24915 5185622..5186275 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HBJ33_RS24920 5186272..5186463 - 192 WP_002911395.1 YebW family protein -
HBJ33_RS24925 5186561..5186800 - 240 WP_002911393.1 YebV family protein -
HBJ33_RS24930 5186916..5188349 - 1434 WP_179108510.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5110682..5202937 92255


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T157779 NZ_CP053771:5183771-5183873 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT157779 NZ_CP053771:c5183880-5183735 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References