Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2334202..2334436 Replicon chromosome
Accession NZ_CP053751
Organism Shigella sonnei strain 506

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2334332..2334435 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2334202..2334436 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COO90_RS11465 2330757..2331419 - 663 WP_000944256.1 exodeoxyribonuclease X -
COO90_RS11470 2331443..2332099 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
COO90_RS11475 2332201..2332431 - 231 WP_000916763.1 DNA polymerase III subunit theta -
COO90_RS11480 2332570..2332944 + 375 WP_000168735.1 CopC domain-containing protein YobA -
COO90_RS11485 2332948..2333820 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
COO90_RS11490 2333833..2334174 + 342 WP_000976476.1 YebY family protein -
- 2334202..2334436 - 235 - - Antitoxin
- 2334332..2334435 + 104 - - Toxin
COO90_RS11495 2334567..2335643 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
COO90_RS11500 2335680..2335925 - 246 Protein_2233 IS1 family transposase -
COO90_RS11510 2337306..2338061 - 756 WP_001282649.1 IS21-like element ISSso4 family helper ATPase IstB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 2321225..2364041 42816


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T157715 NZ_CP053751:2334332-2334435 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT157715 NZ_CP053751:c2334436-2334202 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References