Detailed information of TA system TA157710

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 5101208..5101730
• Replicon: chromosome
• Accession: NZ_CP053750
• Organism: Chromobacterium sp. Beijing

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HQN78_RS23950
• Protein ID: WP_235086829.1
• Coordinates: 5101208..5101495 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HQN78_RS23955
• Protein ID: WP_019103002.1
• Coordinates: 5101485..5101730 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HQN78_RS23925 (HQN78_23680)	5096520..5096915	+	396	WP_235086823.1	hypothetical protein	-
HQN78_RS23940 (HQN78_23695)	5097255..5098214	-	960	WP_235086826.1	bifunctional helix-turn-helix transcriptional regulator/GNAT family N-acetyltransferase	-
HQN78_RS23945 (HQN78_23700)	5098294..5100972	-	2679	WP_235086827.1	TonB-dependent receptor	-
HQN78_RS23950 (HQN78_23705)	5101208..5101495	-	288	WP_235086829.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HQN78_RS23955 (HQN78_23710)	5101485..5101730	-	246	WP_019103002.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
HQN78_RS23960 (HQN78_23715)	5103262..5103819	-	558	WP_203390919.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
HQN78_RS23965 (HQN78_23720)	5103823..5104860	-	1038	WP_235086831.1	type I-F CRISPR-associated protein Csy3	-
HQN78_RS23970 (HQN78_23725)	5104873..5105871	-	999	WP_235086833.1	type I-F CRISPR-associated protein Csy2	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	5095570..5116415	20845

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11104.85 Da
• Isoelectric Point: 10.1975

>T157710 WP_235086829.1 NZ_CP053750:c5101495-5101208 [Chromobacterium sp. Beijing]
MSYEVVFRVDAEKEWRKLDPSIRQQFAKKLRERAEHPHNPSAKLHGLEGCYKIKLRQTGYRLVYEVDDGKIIIIVVAIGH
RDKNEAYLKAKARQG

Nucleotide

• Length: 288 bp

>T157710 NZ_CP069451:298418-298729 [Escherichia coli]
ATCCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTGTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9183.63 Da
• Isoelectric Point: 4.5972

>AT157710 WP_019103002.1 NZ_CP053750:c5101730-5101485 [Chromobacterium sp. Beijing]
MDLVLADVAVSVTELKRNFAGIMREAAGHPVVILNHNRPEAYLVPAAQYERMMNLLEDIEDAKLVLERRQQPTVKVDLDE
L

Nucleotide

• Length: 246 bp

>AT157710 NZ_CP069451:298730-299020 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG