Detailed information of TA system TA157708

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 2504904..2505421
• Replicon: chromosome
• Accession: NZ_CP053750
• Organism: Chromobacterium sp. Beijing

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HQN78_RS11520
• Protein ID: WP_081575981.1
• Coordinates: 2504904..2505158 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: HQN78_RS11525
• Protein ID: WP_235089578.1
• Coordinates: 2505158..2505421 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HQN78_RS11495	2499923..2500636	+	714	WP_235089573.1	hypothetical protein	-
HQN78_RS11500 (HQN78_11385)	2501271..2501828	+	558	WP_235089574.1	hypothetical protein	-
HQN78_RS11505 (HQN78_11390)	2501822..2502349	+	528	WP_235089575.1	hypothetical protein	-
HQN78_RS11510 (HQN78_11400)	2502704..2504215	+	1512	WP_235089576.1	hypothetical protein	-
HQN78_RS11515 (HQN78_11405)	2504455..2504652	-	198	WP_235089577.1	hypothetical protein	-
HQN78_RS11520 (HQN78_11410)	2504904..2505158	-	255	WP_081575981.1	Txe/YoeB family addiction module toxin	Toxin
HQN78_RS11525 (HQN78_11415)	2505158..2505421	-	264	WP_235089578.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HQN78_RS11530 (HQN78_11420)	2505937..2506413	-	477	WP_235089579.1	peptidylprolyl isomerase	-
HQN78_RS11535 (HQN78_11425)	2506860..2507603	+	744	WP_235089581.1	HNH endonuclease signature motif containing protein	-
HQN78_RS11540 (HQN78_11430)	2507722..2508243	-	522	WP_235089582.1	hypothetical protein	-
HQN78_RS11545 (HQN78_11435)	2508969..2509904	-	936	WP_107799912.1	LysR family transcriptional regulator	-
HQN78_RS11550	2509999..2510157	+	159	WP_235089937.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (3-71)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10169.58 Da
• Isoelectric Point: 8.8727

>T157708 WP_081575981.1 NZ_CP053750:c2505158-2504904 [Chromobacterium sp. Beijing]
MQIKFDDNAWEDYLYWQQSSKPTLKRINALIKDIQRNPFEGIGKPEPLKHQFAGFWSRRIDDEHRLVYAVQSNVLTILQC
RYHY

Nucleotide

• Length: 255 bp

>T157708 NZ_CP069448:c84029-83871 [Escherichia coli]
ATGAAACTACCACGCAGCTCTCTTGTCTGGTGTGTGTTGATCGTGTGTCTCACACTGTTGATATTCACTTATCTGACACG
AAAATCGCTGTGCGAGATTCGTTACAGAGACGGATACAGGGAGGTGGCGGCTTTCATGGCTTACGAATCCGGTAAGTAG

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9736.92 Da
• Isoelectric Point: 5.6293

>AT157708 WP_235089578.1 NZ_CP053750:c2505421-2505158 [Chromobacterium sp. Beijing]
VKALTYSHTRQHLAEVMRQVNEDRAPVIVTTQRGEPVVIMSLADYNALEETAYLTRSPENAKRLADAAARFHSGAVKERT
LLEDEGE

Nucleotide

• Length: 264 bp

>AT157708 NZ_CP069448:c84293-84094 [Escherichia coli]
TCACAACGGATTGCCCGTAAACAGCCTGAATGAGCGAGTTATTTTCAGGAAAAGTGAATGTGGTCAGCGTGCTGGTATAT
GGGCTATGATGTGCCCGGCGCTTGAGGTTTTCTGCCTCATGACGTGAAGGTGGTTTGTTACCGTGTTGTGTGGCAGAAGG
ACAAAAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGC