Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 2045853..2046406 Replicon chromosome
Accession NZ_CP053750
Organism Chromobacterium sp. Beijing

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HQN78_RS09490 Protein ID WP_235089189.1
Coordinates 2046134..2046406 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HQN78_RS09485 Protein ID WP_107799530.1
Coordinates 2045853..2046137 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQN78_RS09460 (HQN78_09370) 2041153..2041752 - 600 WP_235089174.1 type I-E CRISPR-associated protein Cas6/Cse3/CasE -
HQN78_RS09465 (HQN78_09375) 2041727..2042389 - 663 WP_235089183.1 type I-E CRISPR-associated protein Cas5/CasD -
HQN78_RS09470 (HQN78_09380) 2042391..2043527 - 1137 WP_227103833.1 type I-E CRISPR-associated protein Cas7/Cse4/CasC -
HQN78_RS09475 (HQN78_09385) 2043553..2044086 - 534 WP_235089184.1 type I-E CRISPR-associated protein Cse2/CasB -
HQN78_RS09480 (HQN78_09390) 2044079..2045629 - 1551 WP_235089187.1 type I-E CRISPR-associated protein Cse1/CasA -
HQN78_RS09485 (HQN78_09395) 2045853..2046137 + 285 WP_107799530.1 hypothetical protein Antitoxin
HQN78_RS09490 (HQN78_09400) 2046134..2046406 + 273 WP_235089189.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HQN78_RS09495 (HQN78_09405) 2046516..2049191 - 2676 WP_235089191.1 CRISPR-associated helicase Cas3' -
HQN78_RS09500 (HQN78_09410) 2049466..2050374 - 909 WP_235089193.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10517.19 Da        Isoelectric Point: 6.6332

>T157705 WP_235089189.1 NZ_CP053750:2046134-2046406 [Chromobacterium sp. Beijing]
MKLVWTLEAVSDREAIFDYIAADNPVAALDLDKHFEQQILRLLQHPELGRAGCVAGTREWVLHRHYICVYDVTIDQLRVL
RILHVARQWP

Download         Length: 273 bp

>T157705 NZ_CP069447:4546783-4547040 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACGTACGTTACACGTTCTCGCTAAAGGTGGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGTCAGCCCTATCGAATCAACACTACCGGGCTGAATAACGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11078.44 Da        Isoelectric Point: 7.0204

>AT157705 WP_107799530.1 NZ_CP053750:2045853-2046137 [Chromobacterium sp. Beijing]
MSETTFTFRVDESLKQEFAKIAKLRDRTGAQLLRDFMRDVVRENKEVAEYEQWFRHQVQQGLDQANSGELVEGDEVDARF
AAKRAALRRRMAER

Download         Length: 285 bp

>AT157705 NZ_CP069447:4547052-4547603 [Escherichia coli]
ATGACAGCACACCACTTCACTTTTCAAATCACAGATGAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAACGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCTGCGTTATCGCTGCTGGCCC
GACATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGGGAAATGGATTCACCGCTGATGCAT
ATCCTCGCTCCCCTGGCAGTCATACCGGAATACCAGGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAAGCACTCACCGCT
CAGCCCATGAACGTGACCGGCCACATCCAGTGCGCGCAGGCCCTGATGAAACCGGAGCACTGGCGTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References