Detailed information of TA system TA157705

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-parD/RelE-RHH
• Location: 2045853..2046406
• Replicon: chromosome
• Accession: NZ_CP053750
• Organism: Chromobacterium sp. Beijing

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HQN78_RS09490
• Protein ID: WP_235089189.1
• Coordinates: 2046134..2046406 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: HQN78_RS09485
• Protein ID: WP_107799530.1
• Coordinates: 2045853..2046137 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HQN78_RS09460 (HQN78_09370)	2041153..2041752	-	600	WP_235089174.1	type I-E CRISPR-associated protein Cas6/Cse3/CasE	-
HQN78_RS09465 (HQN78_09375)	2041727..2042389	-	663	WP_235089183.1	type I-E CRISPR-associated protein Cas5/CasD	-
HQN78_RS09470 (HQN78_09380)	2042391..2043527	-	1137	WP_227103833.1	type I-E CRISPR-associated protein Cas7/Cse4/CasC	-
HQN78_RS09475 (HQN78_09385)	2043553..2044086	-	534	WP_235089184.1	type I-E CRISPR-associated protein Cse2/CasB	-
HQN78_RS09480 (HQN78_09390)	2044079..2045629	-	1551	WP_235089187.1	type I-E CRISPR-associated protein Cse1/CasA	-
HQN78_RS09485 (HQN78_09395)	2045853..2046137	+	285	WP_107799530.1	hypothetical protein	Antitoxin
HQN78_RS09490 (HQN78_09400)	2046134..2046406	+	273	WP_235089189.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HQN78_RS09495 (HQN78_09405)	2046516..2049191	-	2676	WP_235089191.1	CRISPR-associated helicase Cas3'	-
HQN78_RS09500 (HQN78_09410)	2049466..2050374	-	909	WP_235089193.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-86)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10517.19 Da
• Isoelectric Point: 6.6332

>T157705 WP_235089189.1 NZ_CP053750:2046134-2046406 [Chromobacterium sp. Beijing]
MKLVWTLEAVSDREAIFDYIAADNPVAALDLDKHFEQQILRLLQHPELGRAGCVAGTREWVLHRHYICVYDVTIDQLRVL
RILHVARQWP

Nucleotide

• Length: 273 bp

>T157705 NZ_CP069447:4546783-4547040 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACGTACGTTACACGTTCTCGCTAAAGGTGGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGTCAGCCCTATCGAATCAACACTACCGGGCTGAATAACGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 11078.44 Da
• Isoelectric Point: 7.0204

>AT157705 WP_107799530.1 NZ_CP053750:2045853-2046137 [Chromobacterium sp. Beijing]
MSETTFTFRVDESLKQEFAKIAKLRDRTGAQLLRDFMRDVVRENKEVAEYEQWFRHQVQQGLDQANSGELVEGDEVDARF
AAKRAALRRRMAER

Nucleotide

• Length: 285 bp

>AT157705 NZ_CP069447:4547052-4547603 [Escherichia coli]
ATGACAGCACACCACTTCACTTTTCAAATCACAGATGAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAACGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCTGCGTTATCGCTGCTGGCCC
GACATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGGGAAATGGATTCACCGCTGATGCAT
ATCCTCGCTCCCCTGGCAGTCATACCGGAATACCAGGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAAGCACTCACCGCT
CAGCCCATGAACGTGACCGGCCACATCCAGTGCGCGCAGGCCCTGATGAAACCGGAGCACTGGCGTGAATAA