Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 1859426..1859957 Replicon chromosome
Accession NZ_CP053748
Organism Massilia sp. erpn

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HPQ68_RS08405 Protein ID WP_255757275.1
Coordinates 1859426..1859686 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HPQ68_RS08410 Protein ID WP_255757276.1
Coordinates 1859691..1859957 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPQ68_RS08385 (HPQ68_08360) 1854522..1855820 - 1299 WP_255757272.1 FAD-dependent oxidoreductase -
HPQ68_RS08390 (HPQ68_08365) 1856390..1857055 - 666 WP_255757273.1 NUDIX domain-containing protein -
HPQ68_RS08395 (HPQ68_08370) 1857173..1858318 + 1146 WP_255758249.1 radical SAM protein -
HPQ68_RS08400 (HPQ68_08375) 1858311..1859435 + 1125 WP_255757274.1 DNA methyltransferase -
HPQ68_RS08405 (HPQ68_08380) 1859426..1859686 - 261 WP_255757275.1 Txe/YoeB family addiction module toxin Toxin
HPQ68_RS08410 (HPQ68_08385) 1859691..1859957 - 267 WP_255757276.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HPQ68_RS08415 (HPQ68_08390) 1860030..1861331 - 1302 WP_255757277.1 transcriptional regulator PtsJ -
HPQ68_RS08420 (HPQ68_08395) 1861407..1862219 + 813 WP_255757278.1 YggS family pyridoxal phosphate-dependent enzyme -
HPQ68_RS08425 (HPQ68_08400) 1862229..1862945 + 717 WP_255757279.1 type 1 glutamine amidotransferase -
HPQ68_RS08430 (HPQ68_08405) 1863121..1863888 + 768 WP_255757280.1 AraC family transcriptional regulator -
HPQ68_RS08435 (HPQ68_08410) 1863932..1864900 + 969 WP_255757281.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10207.68 Da        Isoelectric Point: 7.8431

>T157699 WP_255757275.1 NZ_CP053748:c1859686-1859426 [Massilia sp. erpn]
MRNYTFTLAAWDDYIYWQGQDKKTLKRINELIKAAGRTPFEGIGKPEPLKGNLSGLWSRRIDECNRLVYEVTEHELIIIA
CRYHYE

Download         Length: 261 bp

>T157699 NZ_CP069447:3143340-3143447 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCGTGATTTTCTGGCACGACCTGGCAGCACCGATCCTTGCGGGAATTATTACCGCAGCGAT
TGTTGGCTGGTGGCGTAGCCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9655.93 Da        Isoelectric Point: 6.7242

>AT157699 WP_255757276.1 NZ_CP053748:c1859957-1859691 [Massilia sp. erpn]
MRIINFSDARSNLRSVIDQVVEDADVTVISRRDAPDAVLMSFEHYSSLIETVHLLSSPANAAHLAKSIAQARAGKAQRRK
LIEPADAE

Download         Length: 267 bp

>AT157699 NZ_CP069447:c3143284-3143223 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTGACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References