Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1854019..1854472 Replicon chromosome
Accession NZ_CP053746
Organism Pseudomonas graminis strain PgKB30

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FX982_RS08440 Protein ID WP_172610317.1
Coordinates 1854203..1854472 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FX982_RS08435 Protein ID WP_172610316.1
Coordinates 1854019..1854213 (+) Length 65 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FX982_RS08420 1850622..1852088 + 1467 WP_122534102.1 4-hydroxy-3-polyprenylbenzoate decarboxylase -
FX982_RS08425 1852088..1853056 + 969 WP_172610315.1 CDP-6-deoxy-delta-3,4-glucoseen reductase -
FX982_RS08430 1853269..1853943 + 675 WP_172613006.1 gamma-glutamylcyclotransferase -
FX982_RS08435 1854019..1854213 + 195 WP_172610316.1 antitoxin Antitoxin
FX982_RS08440 1854203..1854472 + 270 WP_172610317.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FX982_RS08445 1854522..1855871 - 1350 WP_172610318.1 glycerol-3-phosphate transporter -
FX982_RS08450 1856089..1857078 + 990 WP_172610319.1 hypothetical protein -
FX982_RS08455 1857075..1858217 - 1143 WP_172610320.1 acyltransferase -
FX982_RS08460 1858473..1859108 + 636 WP_172610321.1 energy transducer TonB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-83)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10530.99 Da        Isoelectric Point: 4.5143

>T157690 WP_172610317.1 NZ_CP053746:1854203-1854472 [Pseudomonas graminis]
MIVEWRPEAVADLWEILEYIDERNPQAAEELYAEIERATSALPEHPYLYRLGRVPNTREIIVHPNYLVIYRLTDGIEILS
VLHARQQYP

Download         Length: 270 bp

>T157690 NZ_CP069447:c1195671-1195294 [Escherichia coli]
ATGAAAACATTACCCGACACACACGTACGGGCGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCAACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7272.12 Da        Isoelectric Point: 7.0128

>AT157690 WP_172610316.1 NZ_CP053746:1854019-1854213 [Pseudomonas graminis]
MSARLSPLVSEFESEEQAARYDAWLRAKVQASLDDPRPNIAHSEAMAELKSRLAAKRDKRSDDR

Download         Length: 195 bp

>AT157690 NZ_CP069447:c1196128-1195748 [Escherichia coli]
ATGTCGGACACACTCCCCGGAACAACGCTTCCCGACGACAACAAAGACCTCCCCTGGTGGGGGCTGCCCTGCGCCGTGAC
ACCTTGTTTTGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGGGGCCGGT
TCAGCAATGCGGATGCATACCATCTGGACCAGGCTTTTCCACTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCGAAAGGGCTGACCTGCGATGCCGACACCCTCGGGTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCTGCGACCGAAACGGAAAGTAACCCTCCGGAATAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References