Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2156807..2157078 Replicon chromosome
Accession NZ_CP053723
Organism Escherichia coli strain CP66-6_Sichuan

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2156937..2157040 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2156807..2157078 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HP433_RS10405 2153363..2154025 - 663 WP_000944256.1 exodeoxyribonuclease X -
HP433_RS10410 2154048..2154704 - 657 WP_021577595.1 carbon-nitrogen hydrolase family protein -
HP433_RS10415 2154806..2155036 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HP433_RS10420 2155175..2155549 + 375 WP_021577594.1 CopC domain-containing protein YobA -
HP433_RS10425 2155553..2156425 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
HP433_RS10430 2156438..2156779 + 342 WP_000976472.1 YebY family protein -
- 2156807..2157078 - 272 - - Antitoxin
- 2156937..2157040 + 104 - - Toxin
HP433_RS10435 2157175..2157831 + 657 WP_106464872.1 protein-serine/threonine phosphatase -
HP433_RS10440 2157832..2158023 - 192 WP_001296140.1 YebW family protein -
HP433_RS10445 2158128..2158364 - 237 WP_001295499.1 DUF1480 family protein -
HP433_RS10450 2158482..2159921 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T157557 NZ_CP053723:2156937-2157040 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT157557 NZ_CP053723:c2157078-2156807 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References