Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2690650..2691197 Replicon chromosome
Accession NZ_CP053698
Organism Empedobacter stercoris strain ES183

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HNV03_RS12905 Protein ID WP_171624020.1
Coordinates 2690898..2691197 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HNV03_RS12900 Protein ID WP_171624019.1
Coordinates 2690650..2690898 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HNV03_RS12885 2687566..2688819 + 1254 Protein_2486 oleate hydratase -
HNV03_RS12890 2688841..2689737 + 897 WP_171622756.1 3-hydroxyacyl-CoA dehydrogenase -
HNV03_RS12895 2690048..2690248 - 201 Protein_2488 transposase -
HNV03_RS12900 2690650..2690898 + 249 WP_171624019.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HNV03_RS12905 2690898..2691197 + 300 WP_171624020.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12181.77 Da        Isoelectric Point: 4.6229

>T157482 WP_171624020.1 NZ_CP053698:2690898-2691197 [Empedobacter stercoris]
MNYKISKQAEIDLENIWLYTFEEWSLEQADYYLDLIIDEIEYISENPKTGKNYNDVRKGYFRSRVKSHFIFYRINIKEEI
VEIIRILHQQMDIESHINE

Download         Length: 300 bp

>T157482 NZ_CP069327:c4387436-4386681 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATATCCGACCGCTCCAGGGGCGCCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGCTGGGGG
TCGCGGTTTGGCCGTCGCCACGAGCCAAGCCTGTTCTACGCCGCGCTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGCGTCCTGTGGAGTGGCATGGTGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9455.69 Da        Isoelectric Point: 10.0048

>AT157482 WP_171624019.1 NZ_CP053698:2690650-2690898 [Empedobacter stercoris]
MAKNTSILLGDYFDNFINSQIKTGKYSSASEVVRAALRMFEHEETKKTELIKELKKGEKSGFSSDFNRESFKQNLHQKYS
AK

Download         Length: 249 bp

>AT157482 NZ_CP069327:c4387939-4387571 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCCGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCTTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References