Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1540521..1541068 Replicon chromosome
Accession NZ_CP053698
Organism Empedobacter stercoris strain ES183

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HNV03_RS07400 Protein ID WP_171624020.1
Coordinates 1540521..1540820 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HNV03_RS07405 Protein ID WP_171624019.1
Coordinates 1540820..1541068 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HNV03_RS07400 1540521..1540820 - 300 WP_171624020.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HNV03_RS07405 1540820..1541068 - 249 WP_171624019.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HNV03_RS07410 1541470..1541670 + 201 Protein_1437 transposase -
HNV03_RS13635 1542133..1542987 + 855 WP_210766878.1 IS5 family transposase -
HNV03_RS13640 1542984..1543259 + 276 WP_210766879.1 hypothetical protein -
HNV03_RS07420 1543493..1544077 + 585 WP_171624011.1 helix-turn-helix transcriptional regulator -
HNV03_RS07425 1544194..1544997 - 804 WP_171624009.1 bacteriocin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12181.77 Da        Isoelectric Point: 4.6229

>T157481 WP_171624020.1 NZ_CP053698:c1540820-1540521 [Empedobacter stercoris]
MNYKISKQAEIDLENIWLYTFEEWSLEQADYYLDLIIDEIEYISENPKTGKNYNDVRKGYFRSRVKSHFIFYRINIKEEI
VEIIRILHQQMDIESHINE

Download         Length: 300 bp

>T157481 NZ_CP069327:3408111-3408689 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAAGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCACCTCGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9455.69 Da        Isoelectric Point: 10.0048

>AT157481 WP_171624019.1 NZ_CP053698:c1541068-1540820 [Empedobacter stercoris]
MAKNTSILLGDYFDNFINSQIKTGKYSSASEVVRAALRMFEHEETKKTELIKELKKGEKSGFSSDFNRESFKQNLHQKYS
AK

Download         Length: 249 bp

>AT157481 NZ_CP069327:3407468-3408022 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References