Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 879678..880190 Replicon chromosome
Accession NZ_CP053698
Organism Empedobacter stercoris strain ES183

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HNV03_RS04265 Protein ID WP_171622163.1
Coordinates 879933..880190 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HNV03_RS04260 Protein ID WP_171622164.1
Coordinates 879678..879932 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HNV03_RS04235 875132..875290 + 159 WP_115000514.1 lmo0937 family membrane protein -
HNV03_RS04240 875354..876568 - 1215 WP_171622167.1 FAD-binding oxidoreductase -
HNV03_RS04245 876756..877598 + 843 WP_188319937.1 alpha/beta hydrolase -
HNV03_RS04250 877602..878153 + 552 WP_188319938.1 lipocalin family protein -
HNV03_RS04255 878246..878797 - 552 WP_038330349.1 ferritin -
HNV03_RS04260 879678..879932 + 255 WP_171622164.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HNV03_RS04265 879933..880190 + 258 WP_171622163.1 Txe/YoeB family addiction module toxin Toxin
HNV03_RS04270 880498..881490 - 993 WP_188319939.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
HNV03_RS04275 881480..882094 - 615 WP_188319940.1 hypothetical protein -
HNV03_RS04280 882374..884506 - 2133 WP_188319941.1 DUF87 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10489.06 Da        Isoelectric Point: 9.5815

>T157480 WP_171622163.1 NZ_CP053698:879933-880190 [Empedobacter stercoris]
MKYIFVDESWEDYLFWQKTDKKKVKRINDLLKDISRTPFTGIGKPEPLKHKYSGFWSRRIDDEHRLIYKYEDGQILIAKC
RFHYD

Download         Length: 258 bp

>T157480 NZ_CP053698:879933-880190 [Empedobacter stercoris]
ATGAAATACATATTCGTAGATGAATCTTGGGAAGATTATTTGTTTTGGCAAAAAACAGACAAAAAAAAAGTCAAACGAAT
CAATGATCTATTAAAAGACATCTCTAGAACACCTTTTACAGGAATAGGGAAGCCAGAGCCTTTAAAACATAAGTATTCGG
GGTTTTGGTCACGAAGAATAGATGATGAACATCGTTTAATATATAAATATGAAGACGGACAAATACTTATTGCTAAATGC
CGTTTTCATTATGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9681.97 Da        Isoelectric Point: 4.6561

>AT157480 WP_171622164.1 NZ_CP053698:879678-879932 [Empedobacter stercoris]
MLIASVSDFRKDLKSYLDRVSKNFETLIINRGKDSGIVVMSLEEYNSLMATNYELSSRINESRLDSAIEKLKSNQSFEKE
LIEE

Download         Length: 255 bp

>AT157480 NZ_CP053698:879678-879932 [Empedobacter stercoris]
ATGTTAATAGCAAGTGTTTCAGATTTTAGAAAAGATTTAAAATCTTATTTAGATAGAGTTTCAAAAAATTTTGAAACTTT
AATTATCAACAGAGGAAAAGATTCTGGTATTGTTGTAATGTCTCTTGAAGAATACAATTCATTAATGGCGACAAACTATG
AATTATCTTCTCGTATCAATGAATCAAGACTTGATTCAGCCATTGAAAAATTAAAAAGTAATCAATCTTTCGAAAAAGAA
TTAATCGAAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References