Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 735993..736488 Replicon chromosome
Accession NZ_CP053676
Organism MAG: Ferrovum myxofaciens isolate S2.4

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HO274_RS03580 Protein ID WP_273121561.1
Coordinates 735993..736256 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HO274_RS03585 Protein ID WP_273121563.1
Coordinates 736246..736488 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HO274_RS03555 (HO274_03545) 731190..733013 + 1824 WP_273121553.1 ATP-binding cassette domain-containing protein -
HO274_RS03560 (HO274_03550) 733230..733850 + 621 WP_273121555.1 response regulator transcription factor -
HO274_RS03565 (HO274_03555) 733989..735179 + 1191 WP_273121557.1 HAMP domain-containing sensor histidine kinase -
HO274_RS03570 (HO274_03560) 735299..735598 + 300 WP_273121559.1 BrnT family toxin -
HO274_RS03575 (HO274_03565) 735582..735848 + 267 WP_031595211.1 BrnA antitoxin family protein -
HO274_RS03580 (HO274_03570) 735993..736256 + 264 WP_273121561.1 BrnT family toxin Toxin
HO274_RS03585 (HO274_03575) 736246..736488 + 243 WP_273121563.1 hypothetical protein Antitoxin
HO274_RS03590 (HO274_03580) 736561..736725 - 165 WP_273121565.1 DUF1778 domain-containing protein -
HO274_RS03595 (HO274_03585) 737077..738264 + 1188 WP_273121567.1 PEP-CTERM sorting domain-containing protein -
HO274_RS03600 (HO274_03590) 738363..738857 + 495 WP_062188186.1 DUF1178 family protein -
HO274_RS03605 (HO274_03595) 738858..739736 - 879 WP_197456444.1 CHAD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10170.77 Da        Isoelectric Point: 9.5622

>T157424 WP_273121561.1 NZ_CP053676:735993-736256 [Ferrovum myxofaciens]
MRTFEFDESKSQANFVKHGINFVGAQLLWNDPMLLEIPAKTEDEPRFLVIGLIYGKHWSAVLTYRGKSIRLISVRRSRVE
EVTLYEK

Download         Length: 264 bp

>T157424 NZ_CP069306:1323196-1323456 [Rhodococcus aetherivorans]
GTGCGGCTGGTGTGGGACGTCAATGCCTGGGAGGACTACCTGTGGTGGCAGACCCAGGATCGGAAGGTATTGAGACGCAT
CAACGCATTGGTACAGGACATCCTGCGCAACGGTAACGAAGGAATCGGCAAGCCTGAGCCGTTGAAACATGATTTCGCAG
GCTATTGGTCCCGGCGCATTACGGATGAACATCGCCTGGTCTACAAGATCACCGACACAGAGGTCCGCATCGCTGCGTGC
CGCTATCACTACGGCCGGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9143.28 Da        Isoelectric Point: 5.6706

>AT157424 WP_273121563.1 NZ_CP053676:736246-736488 [Ferrovum myxofaciens]
MKSETFDSQFDDGTADITASLDLSKARRVLLNPRRVNVDFPSWMIDSLDREAERLGVTRQSIIKVWLAERLEHVSTHSPS

Download         Length: 243 bp

>AT157424 NZ_CP069306:1322933-1323193 [Rhodococcus aetherivorans]
ATGCGAACTATGAGCTACAGCGAATCGCGCGCCCGGTACGCCGAGGTCTTGGACTCTGTCGTCAACGACCGAGAGGAGAT
CGTCATTACCCGCTCGGGCCACGAGCCCGTTGTGATCGTCTCCCTGGCGGACTTCGAGTCGCTGCGGGAAACGGCTTACC
TGATGCGTTCACCGGCGAACGCTCGACGTCTGCTCGACGCGATGGAACGGCTCGAGGCAGGCGAGGGGCAAGTGCACGAA
CTGATCGAGGGTGACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References