Detailed information of TA system TA157420

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 2369180..2369835
• Replicon: chromosome
• Accession: NZ_CP053675
• Organism: MAG: Ferrovum myxofaciens isolate MI1A

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: A0A8F3E1T1
• Locus tag: HO273_RS11810
• Protein ID: WP_062188107.1
• Coordinates: 2369437..2369835 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A8F3DSV8
• Locus tag: HO273_RS11805
• Protein ID: WP_062188108.1
• Coordinates: 2369180..2369440 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	2292505..2496827	204322

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-124)

Antitoxin

• SpoVT-AbrB domain (8-56)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 14718.11 Da
• Isoelectric Point: 8.6116

>T157420 WP_062188107.1 NZ_CP053675:2369437-2369835 [Ferrovum myxofaciens]
MKRYMLDTNTVSHLLKAHPTVARRMVEVPMASLSISAITEGELLFGLAKRPEAKRLHTAVREFLRRVDVLPWDNAISERY
GTVRADMEKQGNILAPLDLLIAAHALSKGAILVTNDQAFGQVANLLLEDWTN

Nucleotide

• Length: 399 bp

>T157420 NZ_CP069303:485862-486185 [Shinella sp. PSBB067]
GTGAAACGCGGCGATTTCGTCATCGTCGCGATCCAGGGCGATTTCGGCAAGCCACGCCCGGCGCTGGTCATTCAGTCGGA
CCTGTTTTCCGAAGCGGCGACAGTAACGGTCCTGATGGTCTCCAGCACTCTTCAGGATGCGCCCCTGCTGCGCATTCCCG
TCGAACCGAGTGTGGGCAACGGCCTCGGCAAGTCGTCCCAGATCATGGTCGACAAGGCCATGACGATCCGGCGCGACAAG
ATCGGCAAGGTCATCGGTACGCTCGACACCGAGACGATGGCGTCGGTCACGCGCAGCCTTGCCCTTTTCCTGGGATTTGC
CTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9897.99 Da
• Isoelectric Point: 4.3410

>AT157420 WP_062188108.1 NZ_CP053675:2369180-2369440 [Ferrovum myxofaciens]
MSQVAKLFLNGRSQAVRLPVAYRFDTKEVFIRQDTETGDVILSRKPMDWDGFFSALQGVDGPVDFLDAEERDQGTQNRDP
FEGWRE

Nucleotide

• Length: 261 bp

>AT157420 NZ_CP069303:485644-485865 [Shinella sp. PSBB067]
ATGGCCAAGGCGGTAAGCGAAAGAGTGCAGAAGCGCCGCAACGCGCTGCGGGCGAACGGCCTGCGGCCCGTGCAGATGTG
GCTGCCCGACACGCGTCGTATCGGCTTTGCGGAGGAGTGCGTCCGGCAGGCCAGGAAGATTGCTGTCGCCGAGACGGACG
ACCGCGACCTCGATCGCTTCCTGGATGCGGCCTTCCTCGATCTCGTGGGCTCCGATACGTGA