Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1939791..1939936 Replicon chromosome
Accession NZ_CP053666
Organism Klebsiella pneumoniae strain kpn-241

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1939827..1939929 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1939791..1939936 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPK15_RS09355 1934921..1936981 + 2061 WP_004151449.1 oligopeptidase B -
HPK15_RS09360 1936985..1937644 - 660 WP_002911407.1 exodeoxyribonuclease X -
HPK15_RS09365 1937723..1937953 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HPK15_RS09370 1938066..1938440 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HPK15_RS09375 1938444..1939313 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HPK15_RS09380 1939330..1939668 + 339 WP_002911404.1 YebY family protein -
- 1939791..1939936 - 146 - - Antitoxin
- 1939827..1939929 + 103 - - Toxin
HPK15_RS09385 1940304..1940447 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HPK15_RS09390 1940552..1941520 - 969 WP_004151446.1 VirK/YbjX family protein -
HPK15_RS09395 1941677..1942330 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HPK15_RS09400 1942327..1942518 - 192 WP_002911395.1 YebW family protein -
HPK15_RS09405 1942616..1942855 - 240 WP_002911393.1 YebV family protein -
HPK15_RS09410 1942971..1944404 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T157394 NZ_CP053666:1939827-1939929 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT157394 NZ_CP053666:c1939936-1939791 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References