Detailed information of TA system TA157343

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 4413571..4413932
• Replicon: chromosome
• Accession: NZ_CP053649
• Organism: Xanthomonas axonopodis pv. vasculorum strain NCPPB 796

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: XAV_RS19425
• Protein ID: WP_042824104.1
• Coordinates: 4413571..4413705 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: XAV_RS19430
• Protein ID: WP_042824105.1
• Coordinates: 4413780..4413932 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XAV_RS19410	4410597..4411640	-	1044	WP_146089621.1	MBL fold metallo-hydrolase	-
XAV_RS19415	4411671..4412960	-	1290	WP_042824102.1	tryptophan--tRNA ligase	-
XAV_RS19420	4413129..4413338	-	210	WP_042824103.1	CsbD family protein	-
XAV_RS19425	4413571..4413705	-	135	WP_042824104.1	entericidin A/B family lipoprotein	Toxin
XAV_RS19430	4413780..4413932	-	153	WP_042824105.1	entericidin A/B family lipoprotein	Antitoxin
XAV_RS19435	4414040..4414963	-	924	WP_042824945.1	arginase	-
XAV_RS19440	4415284..4415747	+	464	Protein_3787	roadblock/LC7 domain-containing protein	-
XAV_RS19445	4415824..4416171	+	348	WP_042824948.1	hypothetical protein	-
XAV_RS19450	4416268..4417185	+	918	Protein_3789	hypothetical protein	-
XAV_RS19455	4417182..4417724	+	543	WP_042824107.1	GTPase	-
XAV_RS19460	4418204..4418887	+	684	WP_042824108.1	dTMP kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4532.38 Da
• Isoelectric Point: 9.3487

>T157343 WP_042824104.1 NZ_CP053649:c4413705-4413571 [Xanthomonas axonopodis pv. vasculorum]
MKRAIVLLVLSMWSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Nucleotide

• Length: 135 bp

>T157343 NZ_CP069170:c4811283-4810750 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5137.08 Da
• Isoelectric Point: 8.2782

>AT157343 WP_042824105.1 NZ_CP053649:c4413932-4413780 [Xanthomonas axonopodis pv. vasculorum]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSEGKC

Nucleotide

• Length: 153 bp

>AT157343 NZ_CP069170:c4811560-4811294 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA