Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 905341..907061 Replicon chromosome
Accession NZ_CP053649
Organism Xanthomonas axonopodis pv. vasculorum strain NCPPB 796

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag XAV_RS03930 Protein ID WP_042823651.1
Coordinates 906411..907061 (-) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag XAV_RS03925 Protein ID WP_042823652.1
Coordinates 905341..906411 (-) Length 357 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XAV_RS03905 901219..901545 - 327 WP_042823654.1 hypothetical protein -
XAV_RS03910 901848..903146 - 1299 Protein_769 amidohydrolase family protein -
XAV_RS03915 903143..904535 - 1393 Protein_770 amidohydrolase -
XAV_RS03920 904670..905236 + 567 WP_171891029.1 DUF924 family protein -
XAV_RS03925 905341..906411 - 1071 WP_042823652.1 macro domain-containing protein Antitoxin
XAV_RS03930 906411..907061 - 651 WP_042823651.1 DUF4433 domain-containing protein Toxin
XAV_RS03935 907341..908267 - 927 WP_042823650.1 Grx4 family monothiol glutaredoxin -
XAV_RS03940 908313..909104 + 792 WP_171890768.1 polysaccharide deacetylase family protein -
XAV_RS03945 909247..909918 - 672 WP_042823648.1 class I SAM-dependent methyltransferase -
XAV_RS03950 910352..911011 - 660 WP_042823646.1 SGNH/GDSL hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-216)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 25120.74 Da        Isoelectric Point: 8.4533

>T157341 WP_042823651.1 NZ_CP053649:c907061-906411 [Xanthomonas axonopodis pv. vasculorum]
MSRRYPNLNPQKGLIWRIVHRDNLPWILDNGLHCGNGSVPSHRWVNIGNPELIDKRANHPVPLAPGGLLNDYVPFYFTPF
SPMLRNINTSWGGIQRRTNEEIVILVSSLHHVAARGWPFLFTDSHAYYQLTNFYADLANLDKIDWPLLQARDFRRDQEDP
AKFERYQAEALVHRHLPVDGLLGMVCYTDDMKVSIELQLKARKLALPVYARTDWYF

Download         Length: 651 bp

>T157341 NZ_CP069170:c2738304-2736982 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCTGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 40044.12 Da        Isoelectric Point: 6.3661

>AT157341 WP_042823652.1 NZ_CP053649:c906411-905341 [Xanthomonas axonopodis pv. vasculorum]
MITFTQGNLLQARVEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKQVRTGKMFVTETNELNGPRWIINFPTK
QHWRGDSHIEWIAEGLQDLRFFLIENNVESIAIPPLGAGNGGLDWADVRPLIEESLTGLDTKILVFEPISKYQNVAKRSG
VEKLTPARALIAELVRRYLVLGMECSLLEIQKLAWFLERNIERAGLPTLDLRFSPHKYGPYADRLRHLLNGLDGSYLHCD
KRIGDADPLDVIWFDDARKSFLQAYLKSEAKEYAPVLEATAALIDGFESPFGMELLATVDWLIAQADVSPQVANMREGIR
RWPGGPEAALRKDRLFDDRALSIALERLNSSANMVA

Download         Length: 1071 bp

>AT157341 NZ_CP069170:c2738570-2738304 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References