Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE(toxin)
Location 6491566..6492152 Replicon chromosome
Accession NZ_CP053618
Organism Achromobacter xylosoxidans strain GN008

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HPS43_RS29990 Protein ID WP_173011209.1
Coordinates 6491850..6492152 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HPS43_RS29985 Protein ID WP_054436906.1
Coordinates 6491566..6491853 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPS43_RS29965 6487265..6488188 + 924 WP_006385014.1 ABC transporter permease -
HPS43_RS29970 6488194..6489060 + 867 WP_024069588.1 ABC transporter permease -
HPS43_RS29975 6489118..6490857 + 1740 WP_173011208.1 peptidase M14 -
HPS43_RS29980 6490870..6491307 + 438 WP_006385010.1 acetyltransferase -
HPS43_RS29985 6491566..6491853 + 288 WP_054436906.1 hypothetical protein Antitoxin
HPS43_RS29990 6491850..6492152 + 303 WP_173011209.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HPS43_RS29995 6492195..6492464 - 270 WP_054514854.1 ribbon-helix-helix domain-containing protein -
HPS43_RS30000 6492708..6493235 + 528 WP_173011210.1 sigma-70 family RNA polymerase sigma factor -
HPS43_RS30005 6493321..6494277 + 957 WP_173011300.1 FecR domain-containing protein -
HPS43_RS30010 6494570..6496939 + 2370 WP_173011211.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11337.94 Da        Isoelectric Point: 5.7117

>T157238 WP_173011209.1 NZ_CP053618:6491850-6492152 [Achromobacter xylosoxidans]
VRALRWTPEAIQDREAIYDFIEADSPVAALMLDELLEQQAGRLVDHPGPGRPGRVAGTRELVAHPNYLLIYDVKNDLVRM
LRVLPAARQWPTPDPSSERR

Download         Length: 303 bp

>T157238 NZ_CP069078:c3129205-3128321 [Mycobacterium tuberculosis]
GTGGCCGGTCTGACCCGTGCGCTCGTTGCGCGTCACGCTCTTGGTCGGGCCGAGGCATACGACGCCGCTCTGCTCGACGT
CGCCCAGGACCACCTGCTGTACCTGCTGTCGCAGACCGTCCAGTTCGGCGATAACCGCCTGGTGTTCAAAGGCGGTACCA
GCTTACGGAAGTGCCGGCTGGGCAACGTCGGGCGGTTCTCCACTGATCTGGACTTCAGCGCGCCCGACGATGAGGTCGTG
CTGGAGGTGTGCGAGCTGATCGACGGCGCCCGTGTCGGCGGCTTCGAATTCGGCGTGCAGAGCACACGAGGCGACGGCCG
GCATTGGCAGTTGCGGGTGCGGCACACGGAATTGGGCGAGCCCCGGATCGTCGCCAGCGTCGAGTTCGCACGGCGGCCGT
TGGCTTTGCCGTCTGAGCTGCTCGCATTCATCCAGTTGCCGATCCATAAGGCTTACGGTTTTGGGCTGCCGACACTGCCG
GTCGTGGCAGAAGCGGAAGCCTGCGCAGAGAAACTCGCGCGGTACCGCCGCGTTGCGCTGGCACGGGACCTGTACGACCT
GAACCACTTCGCCTCGCGAACGATTGACGAACCGCTCGTGCGGCGGCTGTGGGTGCTCAAGGTGTGGGGTGATGTCGTCG
ATGACCGGCGCGGCACCCGGCCACTACGCGTCGAAGACGTCCTCGCCGCCCGCAGCGAGCACGACTTCCAGCCCGACTCG
ATCGGCGTGCTGACCCGTCCTGTCGCTATGGCTGCCTGGGAAGCTCGCGTTCGGAAGCGATTTGCGTTCCTCACTGACCT
CGACGCCGACGAGCAGCGGTGGGCCGCCTGCGACGAACGGCACCGCCGCGAAGTGGAGAACGCGCTGGCGGTGCTGCGGT
CCTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10747.07 Da        Isoelectric Point: 11.0787

>AT157238 WP_054436906.1 NZ_CP053618:6491566-6491853 [Achromobacter xylosoxidans]
MSDATFTFRVDEALKNEFAMAAKARDRTGAQLLRDFMREYVQQQQEAAQHDAWFRRQVQAGLDSANAGRLAPAAEVETKF
AARRAATRRRLATSK

Download         Length: 288 bp

>AT157238 NZ_CP069078:c3130095-3129208 [Mycobacterium tuberculosis]
GTGGTGAGCCCAGCCGGCGCCGATCGGCGCATCCCCACGTGGGCGTCACGGGTGGTGTCCGGCCTCGCTCGCGATCGGCC
CGTAGTCGTCACGAAAGAGGATCTGACGCAACGGCTTACAGAGGCTGGGTGTGGACGCGACCCCGACTCCGCCATCCGCG
AACTGCGCCGCATTGGGTGGCTGGTCCAACTGCCGGTGAAAGGCACCTGGGCATTCATTCCCCCCGGCGAGGCCGCCATC
TCGGACCCGTATCTACCGCTGCGCTCGTGGCTGGCCCGTGACCAGAACGCGGGCTTCATGCTGGCCGGTGCATCCGCAGC
GTGGCACCTCGGATACCTGGACCGCCAACCCGACGGCCGCATCCCGATCTGGCTGCCGCCGGCCAAAAGGCTGCCCGACG
GCCTAGCATCGTATGTGTCCGTCGTGCGCATCCCCTGGAACGCGGCGGACACCGCACTGCTGGCTCCGCGTCCCGCGTTG
CTGGTCCGGCGGCGGCTCGACCTCGTCGCGTGGGCGACCGGGTTACCGGCGCTAGGACCAGAAGCATTACTTGTGCAAAT
CGCCACGCGCCCGGCCTCGTTCGGGCCGTGGGCCGACCTTGTCCCCCACCTTGACGACCTCGTCGCCGACTGCAGTGACG
AGCGCCTGGAGCGTCTACTGTCGGGCCGGCCGACATCGGCCTGGCAGCGTGCAAGCTACCTGCTGGACTCGGGCGGTGAA
CCGGCACGAGGCCAGGCGCTGCTGGCCAAGCGGCACACCGAAGTGATGCCGGTGACTCGATTCACCACCGCGCACAGCCG
CGACCGTGGCGAGAGTGTCTGGGCTCCCGAGTATCAGCTTGTCGACGAGCTCGTCGTACCGCTGCTGCGCGTGATCGGCA
AGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References