Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3161809..3162362 Replicon chromosome
Accession NZ_CP053617
Organism Achromobacter xylosoxidans strain GN050

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HPS44_RS14330 Protein ID WP_026384933.1
Coordinates 3162084..3162362 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HPS44_RS14325 Protein ID WP_020925646.1
Coordinates 3161809..3162015 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPS44_RS14310 3158452..3159429 - 978 WP_006386985.1 tripartite tricarboxylate transporter substrate binding protein -
HPS44_RS14315 3159621..3160271 - 651 WP_070782163.1 hypothetical protein -
HPS44_RS14320 3160270..3161715 + 1446 WP_047992431.1 RNA polymerase factor sigma-54 -
HPS44_RS14325 3161809..3162015 + 207 WP_020925646.1 hypothetical protein Antitoxin
HPS44_RS14330 3162084..3162362 + 279 WP_026384933.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HPS44_RS14335 3162541..3162840 + 300 WP_006386990.1 (2Fe-2S)-binding protein -
HPS44_RS14340 3162810..3163730 - 921 WP_173000447.1 LysR family transcriptional regulator -
HPS44_RS14345 3163844..3164758 + 915 WP_173000454.1 DMT family transporter -
HPS44_RS14350 3165183..3165659 + 477 WP_006386993.1 bacterioferritin -
HPS44_RS14355 3165744..3166430 - 687 WP_006386994.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10369.93 Da        Isoelectric Point: 9.5759

>T157231 WP_026384933.1 NZ_CP053617:3162084-3162362 [Achromobacter xylosoxidans]
MLDVSWLQTAADDLAGIISYIAERSPQAARNLRQRIDNAVLSLARHPCRYRAGRVSGTRECVVHPNYVVVYRVTALAIEV
VNIVHARREYPP

Download         Length: 279 bp

>T157231 NZ_CP069078:2863905-2864282 [Mycobacterium tuberculosis]
GTGAAGCTGATCGACACCACCATCGCGGTCGACCACCTTCGCGGCGAACCCGCGGCAGCCGTGCTGCTCGCCGAACTGAT
AAACAACGGTGAGGAGATCGCGGCCAGCGAGCTGGTCCGATTCGAACTCCTCGCCGGTGTGCGGGAAAGCGAACTCGCGG
CGCTCGAGGCCTTCTTCTCGGCAGTGGTGTGGACCCTGGTGACCGAGGACATTGCCCGGATCGGCGGACGACTCGCCCGT
CGATACCGGTCCAGCCACCGCGGTATCGACGACGTGGACTACCTGATCGCTGCGACCGCCATTGTGGTCGACGCCGACCT
GCTCACCACCAATGTGCGCCACTTCCCGATGTTCCCGGATCTGCAGCCGCCGTACTGA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7659.52 Da        Isoelectric Point: 4.6855

>AT157231 WP_020925646.1 NZ_CP053617:3161809-3162015 [Achromobacter xylosoxidans]
MGPIPSSILSEFETEEQAVSYDRWFRAKVQASLDDPRPAVSHQRVMARIDAIIETACRRQQDPQGGES

Download         Length: 207 bp

>AT157231 NZ_CP069078:2863651-2863908 [Mycobacterium tuberculosis]
ATGCGGACTCAGGTGACCCTGGGCAAAGAGGAGCTTGAGCTGCTCGATCGTGCCGCCAAGGCGAGTGGCGCATCGCGGTC
CGAACTCATCCGACGCGCAATTCACCGTGCCTACGGGACTGGATCCAAGCAGGAACGGCTCGCCGCGCTCGACCACAGCC
GTGGCTCGTGGCGAGGACGGGACTTCACCGGCACCGAGTATGTCGACGCCATTCGGGGCGACCTCAACGAACGACTTGCT
CGGCTCGGTCTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References