Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE(toxin)
Location 700509..701095 Replicon chromosome
Accession NZ_CP053617
Organism Achromobacter xylosoxidans strain GN050

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HPS44_RS03005 Protein ID WP_054507205.1
Coordinates 700793..701095 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HPS44_RS03000 Protein ID WP_054436906.1
Coordinates 700509..700796 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPS44_RS02980 696201..697124 + 924 WP_006385014.1 ABC transporter permease -
HPS44_RS02985 697130..697996 + 867 WP_172999624.1 ABC transporter permease -
HPS44_RS02990 698054..699793 + 1740 WP_150100742.1 peptidase M14 -
HPS44_RS02995 699806..700243 + 438 WP_006385010.1 acetyltransferase -
HPS44_RS03000 700509..700796 + 288 WP_054436906.1 hypothetical protein Antitoxin
HPS44_RS03005 700793..701095 + 303 WP_054507205.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HPS44_RS03010 701147..701353 - 207 WP_053514712.1 hypothetical protein -
HPS44_RS03015 701350..701925 - 576 WP_026384566.1 GNAT family N-acetyltransferase -
HPS44_RS03020 702100..702735 - 636 WP_172999625.1 methyltransferase domain-containing protein -
HPS44_RS03025 702732..704282 - 1551 WP_172999626.1 lytic murein transglycosylase -
HPS44_RS03030 704385..705026 - 642 WP_198918227.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11252.79 Da        Isoelectric Point: 5.6016

>T157228 WP_054507205.1 NZ_CP053617:700793-701095 [Achromobacter xylosoxidans]
VRALRWTPEAIQDREAIYDFIEADSPVAALMLDELLEQQAGRLVDHPGLGRPGRVAGTRELVAHPNYLLIYDVTNDLVRM
LRVLHAARQWPTPDSSPGNR

Download         Length: 303 bp

>T157228 NZ_CP069078:2803404-2803829 [Mycobacterium tuberculosis]
GTGGCGCTGCTCGACGTCAACGCATTGGTCGCGCTGGCGTGGGACTCACACATCCACCACGCCCGGATCCGCGAGTGGTT
TACCGCCAACGCCACGCTCGGCTGGGCGACTTGCCCGCTCACCGAAGCCGGCTTCGTGCGGGTGTCGACGAACCCAAAAG
TACTTCCCAGCGCGATCGGGATCGCAGACGCTCGACGGGTCCTCGTGGCACTACGCGCCGTGGGAGGCCACCGCTTCCTG
GCTGACGACGTATCGCTCGTCGATGACGATGTTCCGTTGATCGTCGGTTATCGCCAGGTGACCGACGCCCATCTGCTGAC
ACTCGCCCGCCGGCGCGGCGTCCGCCTGGTCACCTTCGACGCCGGTGTCTTCACCCTCGCCCAACAACGCCCCAAGACGC
CAGTGGAGCTGCTGACCATCCTCTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10747.07 Da        Isoelectric Point: 11.0787

>AT157228 WP_054436906.1 NZ_CP053617:700509-700796 [Achromobacter xylosoxidans]
MSDATFTFRVDEALKNEFAMAAKARDRTGAQLLRDFMREYVQQQQEAAQHDAWFRRQVQAGLDSANAGRLAPAAEVETKF
AARRAATRRRLATSK

Download         Length: 288 bp

>AT157228 NZ_CP069078:2803177-2803398 [Mycobacterium tuberculosis]
GTGCGAACGACACTTGACCTTGACGACGATGTGATCGCCGCGGCACGTGAACTTGCCTCCAGCCAGCGCCGCTCGCTCGG
CTCGGTGATTTCCGAACTCGCACGCCGTGGTCTCATGCCCGGACGCGTCGAGGCTGACGACGGGCTGCCGGTGATCCGCG
TTCCAGCCGGGACCCCGCCGATCACACCGGAGATGGTCCGTCGCGCGCTCGATGAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References